Evidence map›Paper›PMID 41160608›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Genomic and insulin-mediated control of metabolic homeostasis by the mosquito ecdysone-induced gene E93.

Xueli Wang, Danqian Geng, Kai Shi, Qi Qi, Xiangyang Lyu, Xiaomei Sun, Alexander S Raikhel, Zhen Zou

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xueli WangState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Danqian GengState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Kai ShiState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Qi QiState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Xiangyang LyuState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Xiaomei SunState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Alexander S RaikhelDepartment of Entomology, University of California, Riverside, CA 92521.ORCID 0000-0003-2082-2821
Zhen ZouState Key Laboratory of Animal Biodiversity Conservation and Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0003-3550-7656

Funding

The role of mosquito microRNAs in blood digestion.R01AI113729 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI RAIKHEL, ALEXANDER SIMEON · 2014 to 2023
$4.1M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) RO1 AI 113729National Key Research and Development Program of China 2024YFC2607505NIAID NIH HHS R01 AI113729NSF of China 32370518NSF of China 32370522
6 · The paper itself

Abstract

Ecdysone-induced protein 93 (E93) is an adult specifier that governs insect pupal-adult conversion. It affects the reproductive transition in adult

Indexed as

AedesEcdysoneHomeostasisInsect ProteinsInsulinAnimalsGlycogen Synthase Kinase 3 betaProto-Oncogene Proteins c-aktSignal TransductionEcdysoneGlycogen Synthase Kinase 3 betaInsect ProteinsInsulinProto-Oncogene Proteins c-aktE93insulinmetabolic reprogrammingreproduction

Identifiers

PMID41160608
PMCPMC12595457

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.