Inherited Peripheral Neuropathies.

Ryan Castoro, Kathryn R Moss

Abstract readReview

In one paragraph

Review in Neurologic clinics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Spectrum of Hereditary Neuropathies in Adult Patients From Serbia.Journal of the peripheral nervous system : JPNS · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ryan CastoroDepartment of Physical Medicine and Rehabilitation, University of Missouri, Columbia, MO, USA; NextGen Precision Health, University of Missouri, 1030 Hitt Street, Columbia, MO 65211, USA.

Kathryn R MossDepartment of Physical Medicine and Rehabilitation, University of Missouri, Columbia, MO, USA; NextGen Precision Health, University of Missouri, 1030 Hitt Street, Columbia, MO 65211, USA. Electronic address: kmoss@missouri.edu.

Funding

Function and Regulation of PMP22 in CMT1A and HNPPK22NS125057 · NINDS · UNIVERSITY OF MISSOURI-COLUMBIA · PI MOSS, KATHRYN RENAE · 2021 to 2025

$952k

NINDS NIH HHS K22 NS125057

6 · The paper itself

Abstract

Inherited peripheral neuropathies are a diverse group of genetic disorders marked by progressive degeneration of peripheral motor, sensory, and autonomic nerves. While next-generation sequencing has improved diagnosis, challenges remain, including resolving variants of uncertain significance and addressing 20% to 50% of inherited neuropathy cases without clear diagnoses. Current care for inherited neuropathies focuses on supportive therapies to preserve functional range of motion, strength, and balance. Research into disease-modifying treatments is advancing, but accelerating progress requires continued biomarker discovery and innovative drug delivery strategies. This article highlights the clinical features, diagnostic approaches, treatment options, and emerging research in the field.

Indexed as

Peripheral Nervous System DiseasesHumansCharcot-Marie-Tooth diseaseDistal hereditary motor neuropathyGenetic mutationHereditary motor and sensory neuropathyHereditary sensory neuropathyInherited peripheral neuropathyNeuromuscular disorderPrecision medicine

Identifiers

PMID41161998

DOI10.1016/j.ncl.2025.05.012

PMCPMC13502994

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.