Draft genome of Angelica Biserrata, a traditional Chinese medicinal herb of the Angelica genus (Apiaceae).

objectivesAngelica biserrata (commonly known as "Duhuo"), a traditional Chinese medicinal herb of the genus Angelica within the Apiaceae family, is clinically valued for its therapeutic effects in dispelling wind-dampness (a TCM syndrome manifesting as inflammatory arthritis, chronic headaches, and migratory pain) and alleviating arthralgia. Its pharmacological properties are primarily attributed to coumarins, to elucidate the molecular mechanisms underlying coumarin biosynthesis and facilitate the breeding of high-coumarin cultivars, we present the first draft genome assembly and annotation of A. biserrata. The first genome assembly of A. biserrata will provide novel insights into elucidating coumarin biosynthesis and advancing evolutionary biological studies. DATA DESCRIPTION: The genome of A. biserrata was sequenced using PacBio HiFi technology, generating 8.83 million high-fidelity reads with an average length of 14.2 kb (125.34 Gb, sequencing coverage 41 ×). The reads were assembled to give a draft genome of 4.52 Gb with an N50 contig length of 35.72 Mb. Chromosome-scale scaffolding was then performed using 300.87 Gb Hi-C data, resulting in a final genome assembly of 3.89 Gb with improved continuity (contig N50 = 34.42 Mb, scaffold N50 = 325.77 Mb). The genomic integrity was 96.59% (based on the embryophyta database of OrthoDB 10) through the evaluation of universal single copy direct homologous gene (BUSCO). At the same time, 3811.62 Mb long sequences were attached to 11 chromosomes, accounting for 97.86%.