Evidence map›Paper›PMID 41163402›Full record

ReviewGut microbes2025

The role of gut mycobiome in responses to cancer immunotherapy.

Natalia Szóstak, Piotr Kozłowski, Tao Zuo, Anna Philips

Abstract readReview
In one paragraph

Review in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Natalia SzóstakInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań, Poland.ORCID 0000-0001-9933-0496
Piotr KozłowskiInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań, Poland.ORCID 0000-0003-3770-7715
Tao ZuoGuangdong Institute of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0001-8450-5281
Anna PhilipsInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań, Poland.ORCID 0000-0001-5020-8836

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiome has emerged as an important modulator of cancer progression and therapy response, yet the role of its fungal component, the gut mycobiome, remains poorly understood. In this review, we summarize current knowledge on the relationship between intestinal fungi and cancer, with a particular focus on the potential influence of the gut mycobiome on the efficacy of immune checkpoint inhibitors (ICIs). Drawing from both human studies and preclinical models, we discuss evidence linking fungal dysbiosis to altered immune responses and therapy outcomes in cancer patients. Specific fungal taxa, such as

Indexed as

FungiGastrointestinal MicrobiomeImmunotherapyMycobiomeNeoplasmsAnimalsDysbiosisHumansImmune Checkpoint InhibitorsTumor MicroenvironmentImmune Checkpoint Inhibitorscancergut dysbiosisgut fungiGut mycobiotaICBICIimmunotherapymycobiome

Identifiers

PMID41163402
PMCPMC12578317

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.