Evidence map›Paper›PMID 41165343›Full record

ArticlemSystems2025

Multi-omics analysis reveals the mechanism of

Caili Zhang, Yue Gao, Yixuan Huang, Yunyi Qin, Yongxin Li, Qingru Chen, Tiantian Wu, Yujie Zhang, Yan Zhang, Datong Deng and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The Gut-Vagina Axis.Microorganisms · 2026
    Review
  3. Foods (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Caili Zhang *School of Life Sciences, Anhui Medical University, Hefei, Anhui, China.ORCID 0009-0005-5433-3411
Yue Gao *School of Life Sciences, Anhui Medical University, Hefei, Anhui, China.
Yixuan Huang *Department of Clinical Medicine, The First School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, China.
Yunyi QinSchool of Life Sciences, Anhui Medical University, Hefei, Anhui, China.
Yongxin LiSchool of Life Sciences, Anhui Medical University, Hefei, Anhui, China.
Qingru ChenSchool of Life Sciences, Anhui Medical University, Hefei, Anhui, China.
Tiantian WuSchool of Life Sciences, Anhui Medical University, Hefei, Anhui, China.
Yujie ZhangSchool of Life Sciences, Anhui Medical University, Hefei, Anhui, China.
Yan ZhangSchool of Life Sciences, Hefei Normal University, Hefei, Anhui, China.
Datong DengDepartment of Clinical Medicine, The First School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, China.
Binbin HuangSchool of Public Health, Anhui Medical University, Hefei, Anhui, China.ORCID 0009-0008-4571-3908
Mingwei ChenDepartment of Clinical Medicine, The First School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, China.ORCID 0000-0002-8439-0469
Maozhen HanSchool of Life Sciences, Anhui Medical University, Hefei, Anhui, China.ORCID 0000-0002-5958-1941

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) mainly induced by high-fat diets (HFD) is becoming a prevalent and serious metabolic disease worldwide. Although probiotics are considered a treatment for T2DM, the underlying mechanisms and therapeutic effects of the specific strain remain unclear. Thus, elucidating the strain-dependent mechanisms and identifying effective probiotic strains for T2DM management are critically needed. In this study, IMPORTANCE: T2DM is becoming a global health problem linked to poor diet and metabolic disorders. The probiotic

Indexed as

Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Gastrointestinal MicrobiomeLactiplantibacillus plantarumLiverProbioticsAnimalsBlood GlucoseDiet, High-FatMaleMiceMice, Inbred C57BLMultiomicsBlood Glucosegut microbiotaLactobacillus plantarummulti-omicsT2DM

Identifiers

PMID41165343
PMCPMC12625740

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.