Evidence map›Paper›PMID 41165729›Full record

ArticleeLife2025

Companion cells with high florigen production express other small proteins and reveal a nitrogen-sensitive

Hiroshi Takagi, Shogo Ito, Jae Sung Shim, Akane Kubota, Andrew K Hempton, Nayoung Lee, Takamasa Suzuki, Jared S Wong, Chansie Yang, Christine T Nolan and 10 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Regulatory DNA Sequences Controlling Gene Expression in Leaf Phloem Cells.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Hiroshi TakagiDepartment of Biology, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0003-0321-0284
Shogo ItoDepartment of Biology, University of Washington, Seattle, United States.
Jae Sung ShimDepartment of Biology, University of Washington, Seattle, United States.
Akane KubotaDepartment of Biology, University of Washington, Seattle, United States.
Andrew K HemptonDepartment of Biology, University of Washington, Seattle, United States.
Nayoung LeeDepartment of Biology, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0002-0353-6455
Takamasa SuzukiDepartment of Biological Chemistry, College of Bioscience and Biotechnology, Chubu University, Kasugai, Japan.
Jared S WongDepartment of Biology, University of Washington, Seattle, United States.
Chansie YangDepartment of Biology, University of Washington, Seattle, United States.
Christine T NolanDepartment of Biology, University of Washington, Seattle, United States.
Kerry L BubbDepartment of Genome Sciences, University of Washington, Seattle, United States.
Cristina M AlexandreDepartment of Genome Sciences, University of Washington, Seattle, United States.
Daisuke KuriharaInstitute for Advanced Research (IAR), Nagoya University, Nagoya, Japan.ORCID https://orcid.org/0000-0003-2703-0405
Yoshikatsu SatoInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Nagoya, Japan.ORCID https://orcid.org/0000-0002-4967-2698
Yasuomi TadaCenter for Gene Research, Nagoya University, Nagoya, Japan.
Takatoshi KibaGraduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan.ORCID https://orcid.org/0000-0001-8651-0404
Jose L Pruneda-PazSchool of Biological Sciences, University of California San Diego, La Jolla, United States.
Christine QuietschDepartment of Genome Sciences, University of Washington, Seattle, United States.
Josh T CuperusDepartment of Genome Sciences, University of Washington, Seattle, United States.
Takato ImaizumiDepartment of Biology, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0001-9396-4412

Funding

Molecular Mechanisms of Seasonal Time MeasurementR01GM079712 · NIGMS · UNIVERSITY OF WASHINGTON · PI IMAIZUMI, TAKATO · 2007 to 2022
$3.5M
Understanding gene regulation in contextR35GM139532 · NIGMS · UNIVERSITY OF WASHINGTON · PI Christine Queitsch · 2021 to 2026
$3.3M
Japan Society for the Promotion of Science 24K18139Ministry of Education, Culture, Sports, Science and Technology JP20H05910Ministry of Education, Culture, Sports, Science and Technology JP22H04978National Science Foundation 1755452National Science Foundation 2240888NIGMS NIH HHS R01 GM079712NIGMS NIH HHS R01GM079712NIGMS NIH HHS R35 GM139532NIGMS NIH HHS R35GM139532
6 · The paper itself

Abstract

The precise onset of flowering is crucial for successful reproduction. In longer days, the florigen gene

Indexed as

ArabidopsisArabidopsis ProteinsFlorigenGene Expression Regulation, PlantNitrogenRepressor ProteinsFlowersPhloemPlant LeavesArabidopsis ProteinsFlorigenFT protein, ArabidopsisNitrogenRepressor ProteinsA. thalianaBROTHER OF FT AND TFL1FLOWERING LOCUS TNITRATE-INDUCIBLE GARP-TYPE TRANSCRIPTIONAL REPRESSOR 1photoperiodic floweringplant biologySingle nuclei RNA-seq

Identifiers

PMID41165729
PMCPMC12575000

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.