Evidence map›Paper›PMID 41166549›Full record

ArticleACS infectious diseases2025

Targeting the Rift Valley Fever Virus Polymerase: Resistance Mechanisms and Structural Insights.

Michal Král', Amiyaranjan Das, Tomáš Kotačka, Anna Blahošová, Veronika Liščáková, Jan Hodek, Jan Konvalinka, Gabriel Demo, Milan Kožíšek

Abstract read
In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michal Král'Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, 166 10 Prague 6, Czech Republic.
Amiyaranjan DasCentral European Institute of Technology, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic.
Tomáš KotačkaInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, 166 10 Prague 6, Czech Republic.
Anna BlahošováInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, 166 10 Prague 6, Czech Republic.
Veronika LiščákováInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, 166 10 Prague 6, Czech Republic.ORCID 0000-0002-8606-8625
Jan HodekInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, 166 10 Prague 6, Czech Republic.
Jan KonvalinkaInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, 166 10 Prague 6, Czech Republic.
Gabriel DemoCentral European Institute of Technology, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic.ORCID 0000-0002-5472-9249
Milan KožíšekInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, 166 10 Prague 6, Czech Republic.ORCID 0000-0002-9476-3409

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rift Valley fever virus (RVFV) is an arbovirus from the

Indexed as

Antiviral AgentsDrug Resistance, ViralRift Valley fever virusRNA-Dependent RNA PolymeraseViral ProteinsAnimalsCryoelectron MicroscopyEnzyme InhibitorsHumansModels, MolecularMutationRift Valley FeverVirus ReplicationAntiviral AgentsEnzyme InhibitorsRNA-Dependent RNA PolymeraseViral ProteinsantiviralsL proteinpolymerase inhibitorsresistance mutationsRift Valley fever virusstructural insights

Identifiers

PMID41166549
PMCPMC12624712

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.