Evidence map›Paper›PMID 41168544›Full record

ReviewThe AAPS journal2025

From Liquid SNEDDS to Solid SNEDDS: A Comprehensive Review of Their Development and Pharmaceutical Applications.

Sandrine Tanga, Poornima Ramburrun, Marique Aucamp

Abstract readReview
PubMed Publisher
In one paragraph

Review in The AAPS journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sandrine TangaSchool of Pharmacy, Faculty of Natural Sciences, University of the Western Cape, Bellville, 7535, South Africa.ORCID 0000-0002-4804-3005
Poornima RamburrunWits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa.ORCID 0000-0003-3385-155X
Marique AucampSchool of Pharmacy, Faculty of Natural Sciences, University of the Western Cape, Bellville, 7535, South Africa. maucamp@uwc.ac.za.ORCID 0000-0003-2561-4458

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The liquid and solid formulations of self-nano-emulsifying drug delivery systems (SNEDDS) have garnered significant attention in the pharmaceutical field for their ability to enhance the solubility and absorption of hydrophobic drugs. While both liquid and solid SNEDDS result in improved bioavailability; portability, patient compliance, desired administration route, and ease of preparation are some factors that contribute to the decision-making of the final SNEDDS dosage form. This review provides a comprehensive analysis of SNEDDS formulations in the liquid and solid state, including production and performance factors that researchers ought to consider when developing their final dosage form. We investigate excipient characteristics, stability concerns, liquid-to-solid preparation methods and their challenges, and in vivo and in vitro comparisons of both dosage forms. Finally, we explore the potential of artificial intelligence in the design of SNEDDS formulations.

Indexed as

Drug Delivery SystemsDrug DevelopmentAnimalsArtificial IntelligenceBiological AvailabilityChemistry, PharmaceuticalDrug CompoundingEmulsionsExcipientsHumansHydrophobic and Hydrophilic InteractionsPharmaceutical PreparationsSolubilityEmulsionsExcipientsPharmaceutical Preparationsliquid SNEDDSnano-emulsionself-nano-emulsifying drug delivery system (SNEDDS)solid SNEDDS

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.