Evidence map›Paper›PMID 41169534›Full record

ArticleResearch and practice in thrombosis and haemostasis2025

Plasminogen mutation-associated thrombotic microangiopathy and role of anticoagulation: a single institution case series.

Shreya Agarwal, Nicola Pozzi, Senthil Sukumar, Camila Masias, Anuja Java, Spero Cataland

Abstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shreya AgarwalDivision of Hematology, Department of Pediatrics, University of California, San Francisco, California, USA.
Nicola PozziDepartment of Biochemistry and Molecular Biology, St. Louis University School of Medicine, St. Louis, Missouri, USA.
Senthil SukumarDivision of Hematology/Oncology, Department of Internal Medicine, Baylor College of Medicine, Houston, Texas, USA.
Camila MasiasMiami Cancer Institute, Baptist Health South Florida, Miami, Florida, USA.
Anuja JavaDivision of Nephrology, Department of Internal Medicine, Washington University, St. Louis, Missouri, USA.
Spero CatalandDivision of Hematology, Department of Internal Medicine, Ohio State University, Columbus, Ohio, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Knowledge gaps exist regarding the role of coagulation pathway mutations such as those in the plasminogen ( Objectives: This study aims to describe the unique phenotypic features of patients with Methods: This was a single-center retrospective study of patients with TMA in whom genetic testing was performed between 2011 and 2023. Data were collected regarding demographics, clinical features at their first presentation, renal outcomes, genetic mutations, and recurrence for those who were found to have a Results: Over the 12-year study period, we identified 6 individuals in our TMA cohort with Conclusion: Patients with

Indexed as

anticoagulationcomplement blockadeeculizumabplasminogen mutationthrombotic microangiopathy

Identifiers

PMID41169534
PMCPMC12570182

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.