Evidence map›Paper›PMID 41170007›Full record

ArticleRSC advances2025

Application of a Sonogel-Carbon electrode modified with gold nanoparticles synthesized through a green technique and pine leaf extract for the simultaneous determination of neurotransmitters.

Asma Blel, Juan José García-Guzmán, Laura Cubillana-Aguilera, José María Palacios-Santander, Chérif Dridi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Asma BlelNANOMISENE Laboratory, LR16CRMN01, Centre for Research on Microelectronics and Nanotechnology (CRMN) of Technopole of Sousse B. P334, 4054 Sahloul Sousse Tunisia Cherif.Dridi@crmn.rnrt.tn.
Juan José García-GuzmánInstitute of Research on Electron Microscopy and Materials (IMEYMAT), Department of Analytical Chemistry, Faculty of Sciences, Campus de Excelencia Internacional del Mar (CEIMAR), University of Cadiz, Campus Universitario de Puerto Real Polígono del Río San Pedro S/N, 11510 Puerto Real Cadiz Spain josem.palacios@uca.es.
Laura Cubillana-AguileraInstitute of Research on Electron Microscopy and Materials (IMEYMAT), Department of Analytical Chemistry, Faculty of Sciences, Campus de Excelencia Internacional del Mar (CEIMAR), University of Cadiz, Campus Universitario de Puerto Real Polígono del Río San Pedro S/N, 11510 Puerto Real Cadiz Spain josem.palacios@uca.es.ORCID https://orcid.org/0000-0002-3559-2697
José María Palacios-SantanderInstitute of Research on Electron Microscopy and Materials (IMEYMAT), Department of Analytical Chemistry, Faculty of Sciences, Campus de Excelencia Internacional del Mar (CEIMAR), University of Cadiz, Campus Universitario de Puerto Real Polígono del Río San Pedro S/N, 11510 Puerto Real Cadiz Spain josem.palacios@uca.es.ORCID https://orcid.org/0000-0001-5407-1208
Chérif DridiNANOMISENE Laboratory, LR16CRMN01, Centre for Research on Microelectronics and Nanotechnology (CRMN) of Technopole of Sousse B. P334, 4054 Sahloul Sousse Tunisia Cherif.Dridi@crmn.rnrt.tn.ORCID https://orcid.org/0000-0002-7219-3740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper reports a Sonogel-Carbon electrode modified with pine leaf extract-derived gold sononanoparticles (AuSNPs) for the simultaneous detection of serotonin (5-HT) and dopamine (DA), key neurotransmitters in human health. To our knowledge, this is the first time AuSNPs have been greenly synthesized using pine leaf extract coupled with ultrasound technology in only a few minutes. The obtained AuSNPs (56 ± 14 nm) were characterized through several techniques: UV/vis spectroscopy, Fourier infrared spectroscopy, X-ray energy dispersive spectroscopy, and electron microscopy. The green AuSNPs were drop-cast onto the Sonogel-Carbon electrode (SNGCE) for the simultaneous determination of DA and 5-HT. The proposed sensor exhibited low limits of detection, good sensitivity (421.80 pM for DA and 192.55 pM for 5-HT), and reproducibility (RSD 4%). Proof of concept was demonstrated by their successful detection in human blood serum, obtaining recovery rates close to 100% for both analytes in all cases, demonstrating that this sensor has great potential for applications in neurodegenerative diseases and early-stage cancer diagnosis.

Identifiers

PMID41170007
PMCPMC12571160

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.