Evidence map›Paper›PMID 41173971›Full record

Trial reportScientific reports2025

Of the article: Microbiological assessment of a herbal mouth rinse for treating chronic generalized periodontitis.

Svetlana Razumova, Sergey Panov, Anna Marakhova, Irina Koroleva, Ekaterina Mikhailova, Anzhela Brago, Haydar Barakat

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Svetlana RazumovaDepartment of Propedeutics of Dental Diseases, Medical Institute, Peoples' Friendship University of Russia named after Patrice Lumumba (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, Russian Federation.
Sergey PanovDepartment of Propedeutics of Dental Diseases, Medical Institute, Peoples' Friendship University of Russia named after Patrice Lumumba (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, Russian Federation.
Anna MarakhovaInstitute of Biochemical Technology and Nanotechnology, Peoples' Friendship University of Russia named after Patrice Lumumba (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, Russian Federation.
Irina KorolevaDepartment of Molecular Microbiology, Institute of Experimental Medicine, Saint Petersburg, acad. Pavlov Street, 12, Saint Petersburg, 197022, Russian Federation.
Ekaterina MikhailovaDepartment of Conservative Dentistry, Saint Petersburg State University, Universitetskaya Embankment, 7-9, Saint Petersburg, 199034, Russian Federation.
Anzhela BragoDepartment of Propedeutics of Dental Diseases, Medical Institute, Peoples' Friendship University of Russia named after Patrice Lumumba (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, Russian Federation.
Haydar BarakatDepartment of Propedeutics of Dental Diseases, Medical Institute, Peoples' Friendship University of Russia named after Patrice Lumumba (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, Russian Federation. dr.haydarbarakat@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal diseases remain highly prevalent across age groups, often aggravated by poor oral hygiene, occlusal anomalies, and defective restorations. This study evaluated the effectiveness of Art-Dentale Expert mouthwash against major periodontopathogens in patients with mild chronic generalized periodontitis (CGP) using PCR diagnostics. Thirty-nine patients with CGP were randomized into a main group (Art-Dentale Expert) and a control group (Chlorhexidine). Gingival pocket samples were collected before treatment and at 7 days, 1 month, and 6 months. Four periodontopathogens (P. gingivalis, T. forsythia, T. denticola, and P. intermedia) were analyzed. The results obtained were processed statistically. Both rinses significantly reduced P. gingivalis and T. forsythia at 7 days, with Chlorhexidine showing a sharper initial decline in P. gingivalis. At 6 months, P. intermedia was completely absent in the Art-Dentale Expert group (p = 0.0209), whereas it persisted in 10% of controls. Art-Dentale Expert demonstrated sustained efficacy, particularly against T. denticola and P. intermedia. These findings support its role as an effective adjunct in periodontal therapy.

Indexed as

Chronic PeriodontitisMouthwashesChlorhexidineFemaleHumansMalePorphyromonas gingivalisTreatment OutcomeChlorhexidineMouthwashesChlorhexidineChronic generalized periodontitisHerbal mouthwashPCR diagnosticPeriodontal pathogens

Identifiers

PMID41173971
PMCPMC12578999

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.