Evidence map›Paper›PMID 41174072›Full record

ArticleSocial psychiatry and psychiatric epidemiology2026

The intersection between race/ethnicity and adverse childhood experiences and its association with depression.

Karthik V Rangavajhula, Ahalya Muraleedharan, Ngozi Adaralegbe, Frank Clark, Anusuiya Nagar, Nosayaba Osazuwa-Peters, Oluwole A Babatunde, Eric Adjei Boakye

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Article in Social psychiatry and psychiatric epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Karthik V RangavajhulaDepartment of Chemistry and Biochemistry, College of Arts and Science, University of South Carolina, Columbia, SC, USA.
Ahalya MuraleedharanDepartment of Chemistry and Biochemistry, College of Arts and Science, University of South Carolina, Columbia, SC, USA.
Ngozi AdaralegbeDepartment of Psychiatry and Behavioral Sciences, McGovern Medical School, Houston, TX, USA.
Frank ClarkPrisma Health, Greer, SC, USA.
Anusuiya NagarPrisma Health, Greer, SC, USA.
Nosayaba Osazuwa-PetersDepartment of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, NC, USA.
Oluwole A BabatundePrisma Health, Greer, SC, USA.
Eric Adjei BoakyeDepartment of Public Health Sciences, Henry Ford Health System, One Ford Place, Detroit, MI, 48202, USA. eadjei1@hfhs.org.ORCID http://orcid.org/0000-0001-9163-8103

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe assessed the association between number of adverse childhood experiences (ACEs) and depression among adults and explored the association by race/ethnicity.

methodsWe used data from the 2020 Behavioral Risk Factor Surveillance System (BRFSS) among 127,577 adult respondents (≥ 18 years old). The exposure was the number of ACEs classified as zero, one, two-three, and ≥ four. The outcome was a self-reported history of depression diagnosis (yes/no). Weighted multivariable logistic regression models examined the association between ACEs and depression stratified by race/ethnicity. Each model was adjusted for age, gender, smoking status, income, education, marital status, and body mass index.

resultsIn this sample, 36%, 23%, 21%, and 20% reported having experienced zero, one, two-three, and ≥ four ACEs, respectively. Depression was reported by 19% of survey respondents. There was a significant interaction between the number of ACEs and race/ethnicity, and depression (p = 0.0003), thus, analyses were stratified by race/ethnicity. Respondents who experienced ≥ 4 ACEs had higher odds of reporting depression: non-Hispanic Whites (aOR = 4.07; 95% CI: 3.55, 4.65), non-Hispanic Blacks (aOR = 3.96, 95% CI: 2.68, 5.86), or Hispanics (aOR = 7.73; 95% CI: 4.48, 13.35). Respondents with 2-3 ACEs had higher odds of reporting depression: non-Hispanic Whites (aOR: 2.41, 95% CI. 2.11- 2.76), non-Hispanic Blacks (aOR: 1.94, 95% CI. 1.19- 3.17), and Hispanics (aOR: 2.86, 95% CI. 1.64- 4.98).

conclusionWe found that individuals with two or more ACEs were more likely to report a depression diagnosis, irrespective of race/ethnicity. This finding highlights the need to monitor individuals with an increasing number of ACEs for depression.

Indexed as

Adverse Childhood ExperiencesDepressionEthnicityRacial GroupsAdolescentAdultAgedBehavioral Risk Factor Surveillance SystemBlack or African AmericanFemaleHispanic or LatinoHumansMaleMiddle AgedRisk FactorsSelf ReportACEAdultsAdverse childhood experiencesBRFSSDepressionRacial disparities

Identifiers

PMID41174072
PMCPMC13021715

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.