Engaging migrants and immigrants in genetics research.

Human populations are always moving within and between countries, setting differential patterns of migration. However, there is a lack of representation of migrants and immigrants in genetics research, which hinders scientific discovery and exacerbates health disparities. This Perspective examines challenges to equitable participation and proposes actionable strategies to enhance inclusion. Drawing from a comprehensive review of recruitment approaches, we advocate for community-centered, digitally enhanced and culturally responsive strategies, including partnerships with community organizations, trusted cultural spaces and multilingual outreach. Integrating migrants into research conducted in host countries is both cost-effective and essential for enhancing genetic heterogeneity in study samples, as it allows for the inclusion of globally diverse populations without the logistical and financial burdens of conducting international recruitment. By embracing inclusive, community-driven approaches that reflect the realities of global mobility, the field can produce more generalizable genomic knowledge.