ReviewCurrent opinion in cell biology2025
When two worlds collide: actin dynamics on endomembranes regulates membrane trafficking.
Review in Current opinion in cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Actin-membrane interface stress regulates Arp2/3-branched actin density during lamellipodial protrusion.bioRxiv : the preprint server for biology · 2026Article
- Mechanism of action of two potent LRRC8/VRAC channel inhibitors.Research square · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Membrane trafficking is an essential aspect of cellular physiology, determining the spatial distribution of macromolecules within a cell in response to conditions such as nutrient availability and cellular stress. Much of this trafficking happens at intracellular membrane delimited vesicles and organelles-here referred to as endomembranes. Actin cytoskeletal dynamics contribute to intracellular force production, including fueling aspects of membrane trafficking on endomembranes. Cellular membrane trafficking and actin dynamics have traditionally been studied as separate specializations. Yet, actin networks interact with membranes and contribute to membrane remodeling, organelle motility, and cargo sorting. Here, we propose a conceptual framework for how actin filament networks participate in endomembrane trafficking and describe examples of each of the putative functions. Furthermore, we describe how aberrant actin-endomembrane interactions contribute to disease states and pose some open questions for the field.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.