ReviewWorld journal of gastrointestinal surgery2025
Cholecystectomy and non-alcoholic fatty liver disease: Exploring the hidden connection and implications.
Review in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Hydrogel-Based Therapeutic Strategies for Post-Cholecystectomy NAFLD: Targeting Bile Acid Signaling, Gut Microbiota, Inflammation, and Hepatic Fibrosis.Gels (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cholecystectomy, one of the most common surgical procedures worldwide, is generally considered safe and effective. However, emerging evidence suggests a potential link between cholecystectomy and the development or progression of non-alcoholic fatty liver disease. This article examines the current understanding of this association, focusing on mechanisms such as altered bile acid metabolism, gut microbiota dysbiosis, and changes in lipid homeostasis. It addresses resolved challenges, including short-term metabolic effects, and highlights key unresolved questions, such as the long-term impact on liver health and specific at-risk populations. Finally, the review discusses future research directions and practical strategies for monitoring and managing liver health in patient's post-cholecystectomy, aiming to improve outcomes and guide clinical practice.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.