SynthesisFrontiers in nutrition2025
Effects of curcumin on dyslipidemia and body mass index in metabolic disorders: a systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evaluating the Effects of Nanocurcumin Supplementation in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Endocrinology, diabetes & metabolism · 2026Pooled it
- Effects of Curcumin/Turmeric Supplementation on Kidney Function in Individuals With Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.Endocrinology, diabetes & metabolism · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to investigate the effects of curcumin on blood lipid levels and body mass index (BMI) in patients with metabolic diseases. Methods: A systematic database search identified 587 records, from which 11 randomized controlled trials (RCTs) involving 662 participants were included. The analysis evaluated changes in triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and BMI. Both fixed-effects models (FEM) and random-effects models (REM) were used for statistical analysis. Funnel plot asymmetry tests (Begg and Egger), Baujat, and Galbraith analyses assessed heterogeneity and potential publication bias. Cochrane RevMan (version 2.0) evaluated the risk of bias. Results: Curcumin supplementation significantly reduced TG levels [mean difference (MD): -16.76 mg/dL, REM], TC levels (MD: -10.59 mg/dL, FEM), and BMI (MD: -0.94 kg/m Conclusion: Curcumin effectively reduced levels of TG, TC, and BMI in patients with metabolic diseases. However, its effects on HDL-C and LDL-C were inconsistent and non-significant under random-effects models, indicating limited efficacy for these endpoints. Providing a more detailed context for the variability in lipid outcomes enhances understanding, especially for non-expert audiences.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.