Evidence map›Paper›PMID 41179764›Full record

SynthesisFrontiers in public health2025

Interventions for reducing caregiver burden in chronic dyspnea: a meta-analysis.

Fang Liu, Han Zhang, Shihan Li, Xianshan Wang, Xiaoqing Long, Yang Liu

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fang Liu *Day Surgery Center of General Practice Medical Center, West China Hosptial of Sichuan Universtiy, Chengdu, China.
Han Zhang *Day Surgery Center of General Practice Medical Center, West China Hosptial of Sichuan Universtiy, Chengdu, China.
Shihan LiDay Surgery Center of General Practice Medical Center, West China Hosptial of Sichuan Universtiy, Chengdu, China.
Xianshan WangDay Surgery Center of General Practice Medical Center, West China Hosptial of Sichuan Universtiy, Chengdu, China.
Xiaoqing LongDay Surgery Center of General Practice Medical Center, West China Hosptial of Sichuan Universtiy, Chengdu, China.
Yang LiuDay Surgery Center of General Practice Medical Center, West China Hosptial of Sichuan Universtiy, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Caregivers of patients with chronic respiratory diseases, such as heart failure, chronic obstructive pulmonary disease, and asthma, often experience significant physical, emotional, and psychological strain. This study aims to evaluate the effectiveness of various interventions designed to reduce caregiver burden and improve caregiver well-being. Design: Meta-analysis of randomized controlled trials (RCTs). Methods: A comprehensive literature search was conducted across multiple electronic databases, identifying randomized controlled trials (RCTs) that assessed interventions aimed at reducing caregiver burden in caregivers of chronic dyspnea patients. A total of 25 RCTs, involving 2,425 participants, were included. The included studies evaluated a variety of interventions, including psychological support, education programs, and physical activity. Data were extracted and analyzed using standardized mean differences (SMD) to assess intervention effects, with heterogeneity and publication bias considered. Results: A total of 25 RCTs involving 2,425 participants were included in the meta-analysis. Interventions significantly reduced caregiver burden (SMD = -0.65, 95% CI -0.96 to -0.34) with notable heterogeneity (I Conclusion: Interventions significantly reduce caregiver burden, particularly in emotional, physical, and social aspects, with improvements in family function, stress, and depression. However, no substantial changes were observed in anxiety or quality of life. The evidence quality is moderate, and future studies should focus on improving methodological rigor and exploring long-term effects. Tweetable abstract: Caregivers of chronic respiratory disease patients face significant strain. Our meta-analysis of 25 RCTs (2,425 participants) found that interventions significantly reduce caregiver burden, especially in emotional, physical, and social aspects, improving family function, stress, and depression. However, anxiety and quality of life showed no substantial changes. Future research should focus on long-term effects and methodological rigor. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD420251034352.

Indexed as

Caregiver BurdenCaregiversCost of IllnessDyspneaChronic DiseaseHumansQuality of LifeRandomized Controlled Trials as TopicSocial SupportStress, Psychologicalasthmacaregiver burdenchronic respiratory diseasesCOPDheart failureinterventionsmeta-analysis

Identifiers

PMID41179764
PMCPMC12575251

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.