ReviewFrontiers in medicine2025
Skin manifestations in diabetes-what is new?
Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Crosstalk Between Oxidative Stress, Protein Glycation, and Extracellular Matrix Remodeling in the Skin of Rats with Type 1 Diabetes: Does Insulin Administration Improve Skin Homeostasis?Antioxidants (Basel, Switzerland) · 2026Article
- Regenerative Therapies for Cosmetic Dermatology for Patients with Diabetes Mellitus: Skin Aging, Aesthetic Concerns, and Evidence-Based Best Practices.International journal of molecular sciences · 2026Review
- A Flexible Wearable Glucose Sensor for Noninvasive Diabetes Screening: Functional Equivalence and Model Interpretability.Biosensors · 2026Article
- Towards a standardized diabetic prolonged wound healing model in hairless SKH1 mice.Experimental biology and medicine (Maywood, N.J.) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes is a chronic disease with a continuously increasing prevalence worldwide. Chronic hyperglycaemia results from elevated blood glucose levels due to disturbed insulin secretion and/or action. Diabetes adversely affects the structure and function of micro- and macrovasculature, leading to the failure of various organs and tissues. Diabetes complications affect the kidneys, retina, peripheral nerves, heart, brain, muscle, and skin. Approximately 30% of diabetic patients have cutaneous manifestations, which may be the first sign of metabolic derangement. Skin manifestations strongly associated with diabetes are foot ulcers, diabetic gangrene, diabetic dermopathy, yellow palms and soles, acanthosis nigricans, bullosis diabeticorum, diabetic thick skin, scleredema diabeticorum, and necrobiosis lipoidica. Non-specific symptoms associated with diabetes include acrochordons, rubeosis faciei diabeticorum, eruptive xanthomas, acquired reactive perforating collagenosis, keratosis pilaris, pruritus, vitiligo, granuloma annulare, lichen planus, as well as bacterial and fungal infections. The prompt recognition of skin lesions can initiate early diagnostic testing and timely treatment, minimising long-term complications of diabetes. The use of specialised bioactive dressings in the treatment of diabetic wounds, as well as immunomodulatory and anti-fibrotic therapies in diabetic dermatoses, is a current treatment trend. This review summarises the recent knowledge on the pathogenesis and clinical conditions of cutaneous manifestations related to diabetes mellitus.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.