ArticleFrontiers in medicine2025
Portal vein hemodynamics measured by 4D flow MRI in predicting minimal hepatic encephalopathy in chronic hepatic schistosomiasis patients.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Minimal hepatic encephalopathy (MHE) is a subclinical neuropsychological disorder frequently observed in chronic hepatic schistosomiasis (CHS) patients. Early diagnosis is challenging due to the subtle and nonspecific nature of MHE symptoms. Advances in magnetic resonance imaging (MRI), specifically 4D flow MRI, allow for non-invasive evaluation of portal vein hemodynamic parameters, offering a potential tool for diagnosing MHE. Objective: To evaluate the application of portal vein hemodynamic parameters measured by 4D flow MRI in diagnosing MHE in CHS patients. Methods: This prospective observational study included 118 CHS patients, divided into MHE ( Results: Patients with MHE exhibited significantly lower portal peak velocity ( Conclusion: 4D flow MRI-derived portal vein hemodynamic parameters, particularly portal mean velocity, are significantly associated with MHE in CHS patients. These findings suggest that non-invasive imaging can provide insights for diagnosis and management of MHE, potentially improving clinical outcomes.
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