ArticleJournal of experimental orthopaedics2025
Comparison of knee articular cartilage thickness across sex and age groups in healthy adults.
Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Assessment of morphology, radiopacity gradient and mechanical properties of articular cartilage with contrast-enhanced high-resolution peripheral quantitative computed tomography.Frontiers in bioengineering and biotechnology · 2026Article
- Comparison of knee articular cartilage thickness across sex and age groups in healthy adults.Journal of experimental orthopaedics · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purposes: Cartilage thickness could be a significant biomarker for the early identification of knee osteoarthritis. However, reference data on cartilage thickness across various age groups are still lacking. Consequently, this study aims to establish reference values for cartilage thickness while examining differences related to sex and age groups. Methods: The study included 232 participants. Bilateral measurements of knee articular cartilage thickness were conducted using ultrasound (US) at three anatomical sites: the lateral femoral condyle, medial femoral condyle and intercondylar area. Three readings were taken per site by an experienced radiologist with expertise in musculoskeletal US. The mean cartilage thickness was calculated, and comparisons were performed between sexes using independent samples Results: Male participants demonstrated significantly higher cartilage thickness than females across all examined locations, except the middle area of the right knee. Notable differences among age groups were seen in the right lateral ( Conclusion: Males showed greater cartilage thickness than females across most knee areas. Additionally, age-related variations in cartilage thickness were primarily observed in males, particularly in those of retirement age, while no significant age-related differences were detected in females. These results underscore the importance of considering sex and age when evaluating knee cartilage health using US. Level of Evidence: Level III.
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Registered trials
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