Evidence map›Paper›PMID 41181042›Full record

ArticleWorld journal of orthopedics2025

Emerging neural modulation techniques for the management of phantom limb pain: Evidence from randomized controlled trials.

Ming-Hui Dong, Yu-Qin Yao, Qiong-Yue Cao, Zheng Li, Jian Na

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of orthopedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ming-Hui DongDepartment of Orthopedics, Jinshan Hospital, Fudan University, Shanghai 201508, China.
Yu-Qin YaoCollege of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221000, Jiangsu Province, China.
Qiong-Yue CaoCollege of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221000, Jiangsu Province, China.
Zheng LiCollege of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221000, Jiangsu Province, China.
Jian NaDepartment of Orthopedics, Xuzhou Central Hospital, Xuzhou 221000, Jiangsu Province, China. najian997@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phantom limb pain (PLP), a common sequela of amputation, affects up to 86% of amputees and significantly impairs quality of life. PLP is thought to stem from complex central and peripheral nervous system plasticity. Current treatments, including pharmacological and non-pharmacological approaches, have limited efficacy. Recently, extended reality technologies have emerged as promising tools for PLP management, leveraging immersive sensory input to modulate cortical reorganization. Of note, emerging neural modulation techniques also offer promising alternatives, including peripheral nerve stimulation, repetitive transcranial magnetic stimulation and transcranial direct current stimulation. These approaches demonstrate clinical efficacy in relieving pain, improving functional outcomes and reducing opioid usage. Future research could prioritize large-scale trials to validate the efficacy of nerve stimulation techniques and explore their integration with extended reality technologies for PLP.

Indexed as

Peripheral nerve stimulationPhantom limb painRepetitive transcranial magnetic stimulationTranscranial direct current stimulationTreatments

Identifiers

PMID41181042
PMCPMC12576719

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.