ReviewAnnals of medicine and surgery (2012)2025
Hematological disruptions in HIV-positive individuals with cardiac arrhythmias: a focus on coagulation and inflammation - a narrative review.
Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Prevalence and factors associated with atrial fibrillation among adults with type 2 diabetes mellitus at Hoima Regional Referral Hospital, Western Uganda: a cross-sectional study.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Immune and hematologic alterations associated with CD4AIDS research and therapy · 2026Article
- Coagulation is associated with renal function decline and chronic kidney disease in people living with HIV in South Africa.Frontiers in nephrology · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
HIV infection is linked to hematological disruptions, notably coagulation abnormalities and chronic inflammation, which contribute to the rising prevalence of cardiac arrhythmias in this population. Elevated fibrinogen, factor VIII, and von Willebrand factor levels promote a hypercoagulable state, while cytokines like IL-6 and TNF-α drive persistent inflammation. These factors interact to induce cardiac electrical remodeling, increasing susceptibility to arrhythmias such as atrial fibrillation and ventricular tachycardia. Additionally, HIV-related inflammation accelerates atherosclerosis, further elevating cardiovascular risk. Some antiretroviral therapies exacerbate prothrombotic tendencies, underscoring the importance of close hematological monitoring. Recognizing and addressing these disruptions is essential for preventing arrhythmias and improving outcomes in HIV-positive individuals.
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