Evidence map›Paper›PMID 41182011›Full record

ArticleJournal of the American Heart Association2025

Clinical and Cardiovascular Magnetic Resonance Characteristics of Veteran Male Endurance Athletes With Atrial Fibrillation: VENTOUX-AF.

Wasim Javed, Ioannis Botis, Raluca Tomoaia, Benjamin Brown, Mubein Shabi, Bradley Chambers, Eylem Levelt, Erica Dall'Armellina, Peter Kellman, John Greenwood and 2 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wasim JavedLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust Leeds United Kingdom.ORCID 0000-0002-5677-5708
Ioannis BotisLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust Leeds United Kingdom.
Raluca Tomoaia"Iuliu Hațieganu" University of Medicine and Pharmacy Cluj-Napoca Romania.
Benjamin BrownLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust Leeds United Kingdom.
Mubein ShabiLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust Leeds United Kingdom.
Bradley ChambersLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust Leeds United Kingdom.ORCID 0000-0003-4603-3935
Eylem LeveltBaker Heart and Diabetes Institute & University of Melbourne Melbourne Australia.ORCID 0000-0002-3799-7102
Erica Dall'ArmellinaLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust Leeds United Kingdom.ORCID 0000-0002-2165-7154
Peter KellmanNational Institutes for Health, National Heart, Lung, and Blood Institute Bethesda MD USA.ORCID 0000-0002-9875-6070
John GreenwoodLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust Leeds United Kingdom.ORCID 0000-0002-2861-0914
Sven PleinLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust Leeds United Kingdom.ORCID 0000-0002-0997-4384
Peter SwobodaLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust Leeds United Kingdom.ORCID 0000-0001-7162-7079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOlder male endurance athletes exhibit an increased risk of atrial fibrillation (AF) of which the pathogenesis is unclear. We aimed to determine whether left atrial (LA) remodeling on cardiovascular magnetic resonance, blood pressure during exercise, and bradyarrhythmia on implantable loop recorder monitoring were associated with AF in athletes.

methodsVENTOUX-AF (Cardiac Magnetic Resonance Assessment of Left Atrial Fibrosis in Veteran Endurance Athletes) was a cross-sectional study comparing 39 male athletes with AF (27 symptomatic and 12 detected on implantable loop recorder) aged ≥50 years exercising ≥10 hour/week for ≥15 years with 94 exercise-matched male athletes in sinus rhythm and 33 sedentary male patients with AF. Participants underwent exercise testing and 3-dimensional late-gadolinium enhancement cardiovascular magnetic resonance with LA fibrosis quantification. A total of 106 asymptomatic athletes in sinus rhythm at recruitment received implantable loop recorder to detect incident AF and bradyarrhythmia.

resultsExercise systolic (208.5±29.9 versus 192.4±25.9 mm Hg,

conclusionsHypertensive response to exercise was common in athletes with AF but LA remodeling and fibrosis were not. Further studies are required to determine whether these factors play a role in the pathogenesis of AF in athletes.

Indexed as

AthletesAtrial FibrillationAtrial RemodelingHeart AtriaMagnetic Resonance Imaging, CinePhysical EnduranceVeteransAgedBlood PressureBradycardiaCross-Sectional StudiesElectrocardiography, AmbulatoryExercise TestFibrosisHumansMaleAF in athletesexercise‐induced hypertensionsports cardiology

Identifiers

PMID41182011
PMCPMC12684780

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.