SynthesisClinical obesity2026
Exploring the Relationship Between Obesity, Weight Loss and Health-Related Quality of Life: An Updated Systematic Review of Reviews.
Synthesis in Clinical obesity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exploring the Relationship Between Obesity, Weight Loss and Health-Related Quality of Life: An Updated Systematic Review of Reviews.Clinical obesity · 2026Pooled it
- Effect of Tirzepatide on Health-Related Quality of Life in Japanese Patients With Obesity Disease: Patient-Reported Outcomes From the SURMOUNT-J Study.Diabetes, obesity & metabolism · 2026Trial
- Life following metabolic and bariatric surgery: up to 19 years follow-up, results from a tertiary centre.Surgical endoscopy · 2026Article
- BODY-Q-7D Measures Consensus-Based Patient-Reported Outcomes for the Management of Obesity Treatment.Obesity (Silver Spring, Md.) · 2026Article
- Review
- Years of Experience and Its Association with Indicators of Adiposity and Health-Related Quality of Life in Teachers: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Factors associated with preoperative health-related quality of life in patients undergoing lumbar spine surgery: a multi-ethnic Asian cohort.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Trajectories of Eating Behavior and Health-Related Quality of Life During the First Year After Metabolic Bariatric Surgery: A Longitudinal Study.Healthcare (Basel, Switzerland) · 2026Article
- Beyond the Scale: Setting Goals for Outcomes Beyond Weight in Evidence-based Obesity Treatment.Current obesity reports · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The aim of this systematic literature review (SLR) of reviews was to update the evidence, established in a 2017 SLR, on the impact of obesity and weight loss by various interventions on health-related quality of life (HRQoL). In total, eight SLRs and/or meta-analyses published since 2017 were identified. The results consistently demonstrated a negative association between obesity and HRQoL, with some evidence suggesting poorer HRQoL in people with adverse metabolic profiles. In addition to substantial weight or body mass index reduction, metabolic and bariatric surgery (MBS) or endoscopic bariatric therapies resulted in significant and clinically relevant HRQoL improvements, with pronounced and persistent effects on the physical components in particular. HRQoL typically improved within 1-2 years after MBS and stabilised or deteriorated while remaining above baseline in subsequent years, likely due to weight regain. Evidence for the benefits of exercise interventions on HRQoL was inconclusive. Notably, no SLRs on anti-obesity medications were identified, limiting conclusions on this emerging treatment area. This updated SLR expands on previous findings from the 2017 SLR, providing additional insights into underexplored areas, including the role of metabolic profiles in HRQoL and trends of HRQoL after MBS. Evidence synthesis remains challenging due to heterogeneity in HRQoL measurements used in this field.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.