Evidence map›Paper›PMID 41184668›Full record

ArticleInternal and emergency medicine2026

Are new psychoactive substances driving sudden unexpected deaths and violence among youth in the European countries?

Umberto Tirelli, Salvatore Chirumbolo

Abstract read
PubMed Publisher
In one paragraph

Article in Internal and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Umberto TirelliTirelli Medical Group, Pordenone, Italy and Former Chairman of the Oncology Department at the National Institute of Cancer, Aviano, PN, Italy.
Salvatore ChirumboloDepartment of Engineering for Innovation Medicine, University of Verona, Strada Le Grazie 8, 37134, Verona, Italy. salvatore.chirumbolo@univr.it.ORCID 0000-0003-1789-8307

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sudden unexpected deaths (SUD) and violent behaviours among young people have emerged as urgent public health concerns in Europe, with Italy showing a marked increase in recent years. This study explores the hypothesis that the diffusion of new psychoactive substances (NPS), such as synthetic cathinones (e.g. 3-methylmethcathinone (3-MMC), besides cocaine, may be contributing to these trends. Drawing on European and Italian data, forensic reports, and pharmacological evidence, we conducted exploratory correlation analyses between NPS availability and outcomes including SUD, sexual harassment, and aggression. Significant associations were observed, with strong correlations between synthetic drug entries and both sudden deaths and violence particularly during the COVID-19 pandemic years (e.g. R

Indexed as

Death, SuddenPsychotropic DrugsViolenceAdolescentAlkaloidsCOVID-19EuropeFemaleHumansMaleSubstance-Related DisordersYoung AdultAlkaloidscathinonePsychotropic DrugsCathinonesDrugEuropeSudden deathsViolenceYouth

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.