Evidence map›Paper›PMID 41186019›Full record

ArticleJournal of periodontal research2025

TAM Pathway Receptor Proteins: Differential Expression in Healthy Human Masticatory Mucosa.

Konstantina Vavetsi, Karina Mendes, Ana T P C Gomes, Tiago Marques, Nuno Rosa, Nicholas Mandarano, Fernanda L Schumacher, Dimitris N Tatakis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of periodontal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Konstantina VavetsiDivision of Periodontology, College of Dentistry, The Ohio State University, Columbus, Ohio, USA.
Karina MendesUniversidade Católica Portuguesa, Faculty of Dental Medicine, Center for Interdisciplinary Research in Health (CIIS), Viseu, Portugal.ORCID https://orcid.org/0000-0002-9413-2367
Ana T P C GomesUniversidade Católica Portuguesa, Faculty of Dental Medicine, Center for Interdisciplinary Research in Health (CIIS), Viseu, Portugal.ORCID https://orcid.org/0000-0002-3201-0081
Tiago MarquesUniversidade Católica Portuguesa, Faculty of Dental Medicine, Center for Interdisciplinary Research in Health (CIIS), Viseu, Portugal.ORCID https://orcid.org/0000-0003-2474-4613
Nuno RosaUniversidade Católica Portuguesa, Faculty of Dental Medicine, Center for Interdisciplinary Research in Health (CIIS), Viseu, Portugal.ORCID https://orcid.org/0000-0003-4604-0780
Nicholas MandaranoDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0009-0006-1256-9802
Fernanda L SchumacherDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-5724-8918
Dimitris N TatakisDivision of Periodontology, College of Dentistry, The Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-6327-3610

Funding

The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUL1TR002733 · NCATS · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2018 to 2022
$28.9M
Fundação para a Ciência e a Tecnologia UID/04279NCATS NIH HHS UL1 TR002733NCATS NIH HHS UL1TR002733
6 · The paper itself

Abstract

This cross-sectional histological/immunohistochemical study is the first to investigate the expression of the TAM pathway receptor tyrosine kinases (AXL, MERTK, and TYRO3) in healthy human masticatory mucosa, demonstrating a ubiquitous and tissue compartment-specific expression profile for each receptor.

Indexed as

Mouth MucosaProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesAdultAxl Receptor Tyrosine Kinasec-Mer Tyrosine KinaseCross-Sectional StudiesFemaleHumansImmunohistochemistryMaleMiddle AgedAXL protein, humanAxl Receptor Tyrosine Kinasec-Mer Tyrosine KinaseMERTK protein, humanProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesAxl receptor tyrosine kinasec‐Mer tyrosine kinasemouth mucosapalatereceptor protein‐tyrosine kinasesTYRO3 protein

Identifiers

PMID41186019
PMCPMC12586958

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.