Evidence map›Paper›PMID 41187288›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2025

Ossification of the Posterior Longitudinal Ligament in a Chilean Population: A CT-Based Prevalence Study in Patients Aged 60 Years and Older.

Julio Urrutia, Hugo Demandes, Nicolas Rotman, Pablo Cikutovic

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Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Julio UrrutiaFrom the Department of Orthopaedic Surgery, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile (Dr. Urrutia and Dr. Demandes); the Department of Orthopaedic Surgery, Universidad Austral de Chile (Dr. Rotman); and the Department of Radiology, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile (Dr. Cikutovic).ORCID 0000-0003-1757-1144
Hugo Demandes
Nicolas Rotman
Pablo Cikutovic

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe prevalence of ossification of the posterior longitudinal ligament (OPLL) has been primarily studied in East Asian countries; its prevalence in Western populations remains to be elucidated. We aimed to determine the prevalence of OPLL in a Chilean population aged 60 years and older using fluorine-18 fluorodeoxyglucose positron emission tomography and CT (PET-CT) as screening tool.

methodsWe evaluated patients between 60 and 73 years consecutively studied with PET-CT in a University Hospital. We assessed whole-body CT scans in both sagittal and axial views to detect the presence of OPLL. We used the Mann-Whitney test to analyze continuous variables, the Fisher test for categorical variables, and a logistic regression analysis to determine the independent effect of age and sex on the presence of OPLL.

resultsWe studied 1,009 patients (median age = 66 years); 597 were males (59.17%). Nineteen patients had OPLL, with a prevalence of 1.88% (1.04 to 2.72). OPLL was more prevalent in men (2.68%) than in women (0.73%; P = 0.02). All cases presented cervical involvement; only one had cervical and thoracic OPLL. The median age of patients with OPLL (64 years) and without OPLL (66 years) was not statistically different (P = 0.09). Male sex independently influenced the presence of OPLL (odds ratio = 3.85 [1.11 to 13.33]), age did not (odds ratio = 0.89 [0.78 to 1.02]). DISCUSSION: This is the first study evaluating the prevalence of OPLL in Latin America. It shows a prevalence alike that in non-Asian populations in the United States and lower than the prevalence described in Asian populations.

Indexed as

Ossification of Posterior Longitudinal LigamentAgedChileFemaleHumansMaleMiddle AgedPositron Emission Tomography Computed TomographyPrevalenceTomography, X-Ray Computed

Identifiers

PMID41187288
PMCPMC12551726

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.