Evidence map›Paper›PMID 41187939›Full record

ArticleArquivos de neuro-psiquiatria2025

Genetic and clinical insights into ALS8: exploring the impact of VAPB pathogenic variants in familial amyotrophic lateral sclerosis.

Adriana Helena de Oliveira Reis, Gabriella Pereira de Oliveira Magno, Bruna Guimarães de França Costa, Luna Borges Figalo, Marco Orsini

Abstract read
In one paragraph

Article in Arquivos de neuro-psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adriana Helena de Oliveira ReisUniversidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcântara Gomes, Departamento de Genética, Rio de Janeiro RJ, Brazil.ORCID 0000-0001-7458-131X
Gabriella Pereira de Oliveira MagnoUniversidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcântara Gomes, Departamento de Genética, Rio de Janeiro RJ, Brazil.ORCID 0009-0003-2961-8138
Bruna Guimarães de França CostaUniversidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcântara Gomes, Departamento de Genética, Rio de Janeiro RJ, Brazil.ORCID 0009-0009-1336-1781
Luna Borges FigaloUniversidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcântara Gomes, Departamento de Genética, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-7017-5880
Marco OrsiniUniversidade Iguaçu, Faculdade de Medicina, Programa de Pós-Graduação em Vigilância em Saúde, Nova Iguaçu RJ, Brazil.ORCID 0000-0002-8526-6937

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease leading to progressive muscle weakness and paralysis. Approximately 10% of ALS cases are familial (FALS), with the

Indexed as

Amyotrophic Lateral SclerosisVesicular Transport ProteinsAdultAgedBrazilDisease ProgressionFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedMutationPedigreeVAPB protein, humanVesicular Transport Proteins

Identifiers

PMID41187939
PMCPMC12585906

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.