SynthesisSurgical endoscopy2025
SAGES 2025 systematic review and meta-analysis for fluorescence image-guided gastrointestinal surgery using indocyanine green.
Synthesis in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Protocol digest of a randomized controlled trial comparing transverse colectomy with extended right hemicolectomy for Stage II/III transverse colon cancer: JCOG2304 (TACTICS).Japanese journal of clinical oncology · 2026Article
- Indocyanine green fluorescence navigation for extrahepatic bile duct visualization in laparoscopic cholecystectomy: a prospective cohort study.Annals of medicine and surgery (2012) · 2026Article
- Severe Stercoral Colitis Requiring Extensive Colectomy: A Report of Two Cases.Surgical case reports · 2026Article
- Beyond fluorescence intensity: a Minimum acquisition and reporting standard and emerging technologies for colorectal indocyanine green fluorescence angiography studies.Frontiers in surgery · 2026Article
- Use of Human Amnion/Chorion Membrane as a Protective Barrier in Complicated Diverticulitis Patients Undergoing Colorectal Resections.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFluorescence image-guided surgery (FIGS) using indocyanine green (ICG) enhances intraoperative visualization. Its application spans various surgical fields, yet evidence on its influence on clinical outcomes remains inconsistent. This systematic review was conducted as part of a guideline development process to evaluate the effectiveness of FIGS with ICG across several different surgical applications.
methodsA systematic review was carried out, including a literature search up to October 2022, addressing eight predefined key questions (KQs) on the role FIGS with ICG in thoracic duct identification, detection of distant cancer metastases and primary cancers, lymph node retrieval, and improved evaluation of anastomotic perfusion. The search was extended until September 2024 for colorectal anastomosis application. Eligible studies included randomized controlled trials (RCTs) and comparative observational studies. Meta-analyses were conducted where appropriate. The review is reported following PRISMA 2020 guidelines.
resultsSeven RCTs were pooled and found that FIGS with ICG reduced colorectal anastomotic leak rates (Odds Ratio (OR) 0.58, 95%CI 0.44-0.75). It also facilitated intraoperative changes in the transection point during colorectal anastomoses in RCTs (OR 35.15, 95%CI 8.72-141.77). FIGS with ICG increased lymph node retrieval in gastrointestinal cancer surgeries by 6.32 nodes on average (95%CI 4.43-8.22). Evidence regarding its role in thoracic duct identification, esophageal anastomoses, bariatric surgeries, and pediatric applications remained limited.
conclusionsThis systematic review demonstrates that FIGS with ICG improves outcomes in specific surgical applications, particularly in malignant lymph node retrieval and colorectal anastomotic leak reduction. However, its effectiveness varies depending on the surgical context and clinical question. Further high-quality studies are required to address remaining gaps and inform evidence-based guidelines for broader implementation.
Indexed as
Identifiers
41188413What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.