Evidence map›Paper›PMID 41189578›Full record

ArticleERJ open research2025

Healthcare resource utilisation in patients with exacerbations of COPD and associated cardiovascular events: the EXACOS-CV study.

Nathaniel M Hawkins, Arshdeep K Randhawa, Clementine Nordon, Manisha Talukdar, Suzanne McMullen, J Paul Ekwaru, Tram Pham, Don D Sin

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nathaniel M HawkinsCentre for Cardiovascular Innovation, Division of Cardiology, University of British Columbia, Vancouver, BC, Canada.ORCID https://orcid.org/0000-0003-1286-2014
Arshdeep K RandhawaAstraZeneca Canada Inc., Mississauga, ON, Canada.ORCID https://orcid.org/0000-0002-9487-2488
Clementine NordonGlobal Medical Evidence, AstraZeneca, Cambridge, UK.
Manisha TalukdarAstraZeneca Canada Inc., Mississauga, ON, Canada.
Suzanne McMullenMedlior Health Outcomes Research Ltd, Calgary, AB, Canada.ORCID https://orcid.org/0000-0001-7852-9930
J Paul EkwaruMedlior Health Outcomes Research Ltd, Calgary, AB, Canada.ORCID https://orcid.org/0000-0001-7385-4769
Tram PhamMedlior Health Outcomes Research Ltd, Calgary, AB, Canada.ORCID https://orcid.org/0000-0001-6173-222X
Don D SinDepartment of Medicine (Division of Respirology), University of British Columbia, Vancouver, BC, Canada.ORCID https://orcid.org/0000-0002-0756-6643

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The EXACOS-CV Canada study described and evaluated treatment patterns, healthcare resource utilisation (HCRU), and costs in patients with COPD who experienced a severe cardiovascular (CV) event or death preceded or not preceded by an exacerbation. Methods: This longitudinal, retrospective cohort study included 142 787 individuals with COPD using administrative data from Alberta, Canada. The index event was a first hospitalisation for a CV event or all-cause death during follow-up. COPD-related treatment, HCRU and costs during the 12-month periods before and after the index events were described. Results: From the initial cohort, 43 564 (30.5%) patients with COPD experienced an index event; 15 100 (34.7%) had a COPD exacerbation in the 12 months prior. Patients whose index event was preceded ( Discussion: Patients whose index events were preceded

Identifiers

PMID41189578
PMCPMC12581169

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.