ArticleCureus2025
Ten-Year Death Trends Related to Dementia, Alzheimer's Disease, and Epilepsy in England and Wales (2014-2023): A Descriptive Analysis of National Death Registration Data.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Parental obesity exacerbates cognitive dysfunction and cardiac vulnerability in offspring of an Alzheimer disease model.American journal of physiology. Heart and circulatory physiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDementia, including Alzheimer's disease, and epilepsy are major neurological conditions contributing to mortality in England and Wales. Recent data suggest increasing dementia‑related deaths, particularly in ageing populations, while epilepsy remains a less frequent but significant cause of premature mortality. Methods: This descriptive study analyzed national death registration data from the Office for National Statistics between 2014 and 2023. Deaths attributed to dementia (International Classification of Diseases, Tenth Revision (ICD-10) codes, F01, F03, G30) and epilepsy (ICD-10 codes, G40-G41) were included for individuals aged ≥20 years in England and Wales. Data were cleaned, filtered, and analyzed using Stata Statistical Software: Release 18 (StataCorp LLC., College Station, Texas, United States). Frequencies and percentages were calculated using frequency weights to reflect true death counts, and trends were visualized using line and bar graphs. Results: A total of 622,965 deaths were recorded over the 10‑year period. Dementia and Alzheimer's disease accounted for nearly all deaths (99.98%) as the recorded underlying (primary) cause of death on death certificates, predominantly among females (67.5%) and individuals aged ≥80 years (89.9%). Mortality increased from 2014 (7.7%) to 2018 (11.1%), declined in 2021 (9.2%) during the COVID‑19 pandemic, and rebounded in 2022 (10.5%) and 2023 (10.7%). Conclusion: Dementia‑related mortality in England and Wales remains high and predominantly affects older women. Targeted prevention, improved care pathways, and continued monitoring of post‑pandemic trends are recommended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.