ReviewFrontiers in pharmacology2025
Pain and anesthesia - on fetal nervous system and brain development.
Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Does using narcotics for labor pain relief or undergoing general anesthesia during pregnancy affect fetal neurodevelopment? This is a critical concern for expectant mothers, families, and clinicians alike. While surgical interventions are typically performed during the second trimester-a critical phase for fetal central nervous system development-current research indicates that general anesthesia administered during this period may adversely impact the fetal CNS. How should we balance these risks? This review examines the latest studies on anesthesia's effects on fetal neurodevelopment, exploring relevant mechanisms and characteristics. It aims to provide a comprehensive understanding and propose protective measures to ensure healthy fetal development while maintaining anesthesia safety throughout the entire pregnancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.