SynthesisFrontiers in nutrition2025
Sugar-sweetened beverages and the risk of hyperuricemia and gout: a meta-analysis.
Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The oral und systemic health risks of sugar consumption: an umbrella review.Clinical oral investigations · 2026Pooled it
- Association Between the Planetary Health Diet Index and Serum Uric Acid Levels and Incident Hyperuricemia: Findings From an Iranian Prospective Cohort Study.Food science & nutrition · 2026Article
- Dietary intake and hyperuricemia among US adults: A matched case-control analysis of NHANES 2001-2020.Medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This meta-analysis aimed to investigate the association between sugar-sweetened beverages (SSBs), fructose, and the risk of gout and hyperuricemia. Methods: Following PRISMA guidelines, we systematically searched PubMed, EMBASE, and Cochrane Library for observational studies from inception to March 2025. Adjusted odds ratios (ORs) with 95% confidence intervals (CIs) were pooled using random/fixed-effects models. Subgroup analyses explored sex. Heterogeneity ( Results: A total of 22 studies (235,790 participants) were included. SSB intake significantly increased the risk of hyperuricemia (OR = 1.33, 95% CI: 1.23-1.44) and gout (OR = 1.21; 95% CI 1.11-1.32). Fruit juice (FJ) showed a modest association with hyperuricemia (OR = 1.15, 95% CI: 1.02-1.29) and an increased risk of gout (OR = 1.28; 95% CI 0.96-1.72). Fructose consumption was strongly associated with increased gout risk (OR = 1.66, 95% CI: 1.27-2.18), but its relationship with hyperuricemia was inconsistent (OR = 1.12, 95% CI: 0.85-1.46). DSD showed a modest association with gout (OR = 1.14; 95% CI 0.95-1.35). Subgroup analysis revealed SSB and FJ consumption associated with elevated risks of hyperuricemia in males (SSBs: 1.37; FJ: 1.15) compared to females (SSBs: 1.29; FJ: 1.13). Conclusions: SSB consumption is associated with increased risks of hyperuricemia and gout, particularly in males. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=1040227, PROSPERO (Unique Identifier: CRD420251040227).
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.