Evidence map›Paper›PMID 41191764›Full record

ArticleScience advances2025

Real-time decoding of full-spectrum Chinese using brain-computer interface.

Youkun Qian, Changjiang Liu, Peixi Yu, Xingchen Ran, Shurui Li, Qinrong Yang, Yang Liu, Lei Xia, Yijie Wang, Jianxuan Qi and 6 more

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Youkun QianDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0000-0002-9984-4830
Changjiang Liu2020 X-Lab, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China.ORCID 0000-0003-3627-2334
Peixi YuSchool of Biomedical Engineering, ShanghaiTech University, Shanghai 201210, China.ORCID 0009-0003-5938-8345
Xingchen RanNeuroxess Co. Ltd., Shanghai 200023, China.ORCID 0000-0002-3868-0713
Shurui LiSchool of Biomedical Engineering, ShanghaiTech University, Shanghai 201210, China.ORCID 0009-0007-6371-4069
Qinrong YangNeuroxess Co. Ltd., Shanghai 200023, China.ORCID 0009-0008-3451-9026
Yang LiuNeuroxess Co. Ltd., Shanghai 200023, China.
Lei XiaNeuroxess Co. Ltd., Shanghai 200023, China.
Yijie WangDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.
Jianxuan QiDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0009-0005-9708-6027
Erda Zhou2020 X-Lab, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China.ORCID 0009-0009-8432-0928
Junfeng LuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0000-0002-6091-5742
Yuanning LiSchool of Biomedical Engineering, ShanghaiTech University, Shanghai 201210, China.ORCID 0000-0003-3277-0600
Tiger H TaoNeuroxess Co. Ltd., Shanghai 200023, China.
Zhitao ZhouSchool of Graduate Study, University of Chinese Academy of Sciences, Beijing 100049, China.ORCID 0000-0003-4277-4461
Jinsong WuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0000-0001-7854-9798

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Speech brain-computer interfaces (BCIs) offer a promising means to provide functional communication capacity for patients with anarthria caused by neurological conditions such as amyotrophic lateral sclerosis (ALS) or brainstem stroke. Current speech decoding research has predominantly focused on English using phoneme-driven architectures, whereas real-time decoding of tonal monosyllabic languages such as Mandarin Chinese remains a major challenge. This study demonstrates a real-time Mandarin speech BCI that decodes monosyllabic units directly from neural signals. Using the 256-channel microelectrocorticographic BCI, we achieved robust decoding of a comprehensive set of 394 distinct syllables based purely on neural signals, yielding median syllable identification accuracy of 71.2% in a single-character reading task. Leveraging this high-performing syllable decoder, we further demonstrated real-time sentence decoding. Our findings demonstrate the efficacy of a tonally integrated, direct syllable neural decoding approach for Mandarin Chinese, paving the way for full-coverage systems in tonal monosyllabic languages.

Indexed as

Brain-Computer InterfacesSpeechAdultChinaEast Asian PeopleElectroencephalographyFemaleHumansLanguageMale

Identifiers

PMID41191764
PMCPMC12588286

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.