ArticleCommunications medicine2025
Proof of concept 3D ultrasound strain imaging measuring effect of a ring pessary on avulsed puborectal muscle.
Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlacement or fitting of a ring pessary is one of the treatment options for women with pelvic organ prolapse (POP), resulting from avulsion. To determine the effect of ring pessary use in these women, usually qualitative measures like a patient experience questionnaire is used. However, quantitative functional information could provide additional information about the state of the pelvic floor muscles, such as the puborectal muscle (PRM).
methodsIn this proof-of-concept study, we describe ultrasound (US) strain imaging of PRM to provide functional information. We acquired three-dimensional (3D) US data in women with avulsion, before and after pessary fitting, and subsequently, their strain patterns have been compared. Normalized strain ratios (NSRs) have been calculated for these women to quantitatively indicate the changes in the state of the PRM at maximum contraction, before as well as three months after pessary use.
resultsBefore pessary fitting, the strain ratio was elevated with respect to strain ratios found in women without an avulsion. After pessary fitting, we found that the strain ratio decreased to values close to strain ratios found in women with no avulsion, indicating the benefit of pessary placement. Furthermore, the success of the pessary treatment, as indicated by the NSRs was also reflected in the patient-reported outcome measures (PROMs) from these women.
conclusionsSince, NSRs decreased to more normal values for these women, from before to after pessary treatment, this ratio could be used as an quantitative indicator for the effectiveness of pessary treatment.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.