Evidence map›Paper›PMID 41194513›Full record

ArticleFEBS open bio2026

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node.

Paula M Wagner, César G Prucca, Lucia Boffelli, Virginia A Piqueras, Silvia G Correa, Mariana Maccioni, Mario E Guido

Abstract read
In one paragraph

Article in FEBS open bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paula M WagnerCIQUIBIC - CONICET, Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
César G PruccaCIQUIBIC - CONICET, Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Lucia BoffelliCIBICI - CONICET, Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Virginia A PiquerasCIBICI - CONICET, Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Silvia G CorreaCIBICI - CONICET, Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Mariana MaccioniCIBICI - CONICET, Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Mario E GuidoCIQUIBIC - CONICET, Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.ORCID https://orcid.org/0000-0002-5485-4904

Funding

Agencia Nacional de Promoción Científica y Técnica PICT 2018-1789Agencia Nacional de Promoción Científica y Técnica PICT 2020-0613Agencia Nacional de Promoción Científica y Técnica PICT 3119 2020Consejo Nacional de Investigaciones Científicas y Tecnológicas de la República Argentina (CONICET) PIP 2014Consejo Nacional de Investigaciones Científicas y Tecnológicas de la República Argentina (CONICET) PIP 2021Secretaría de Ciencia y Tecnología de la Universidad Nacional de Córdoba (SeCyT-UNC)
6 · The paper itself

Abstract

Circadian rhythms orchestrate physiological processes, including immune function, across a 24-h cycle. This study investigates the temporal distribution of immune cell populations in healthy mice entrained to a 12:12-h light-dark cycle. Inguinal lymph node (iLN) samples were collected at zeitgeber times (ZT) 0 (lights on) and ZT12 (lights off) to assess immune cell composition. A significantly higher proportion of natural killer T (NKT) cells and neutrophils was observed at ZT0 compared to ZT12, while dendritic cells, macrophages, and natural killer (NK) cells showed no significant temporal variation. Additionally, adaptive immune cells, particularly Programmed cell Death protein 1

Indexed as

Circadian RhythmLymph NodesLymphocytesLymphocyte SubsetsMyeloid CellsAnimalsKiller Cells, NaturalMaleMiceMice, Inbred C57BLadaptive immunitybiological clockcircadian rhythmsinnate immunitylymphoid and myeloid cells

Identifiers

PMID41194513
PMCPMC12955754

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.