Evidence map›Paper›PMID 41194824›Full record

ArticleCureus2025

Nuclear Protein in Testis (NUT) Carcinoma With Nasopharyngeal and Intracranial Involvement: A Case Report.

Natasha Holden, James Park, Chul Chae, Dassaev Vigil, Donald Dennis

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natasha HoldenCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, USA.
James ParkMedical Imaging, Arrowhead Regional Medical Center, Colton, USA.
Chul ChaeMedical Imaging, Arrowhead Regional Medical Center, Colton, USA.
Dassaev VigilMedical Imaging, Arrowhead Regional Medical Center, Colton, USA.
Donald DennisRadiology, Arrowhead Regional Medical Center, Colton, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nuclear protein in testis (NUT) carcinoma is a rare and aggressive malignancy characterized by NUT gene rearrangement. Previously classified as NUT midline carcinoma, this malignancy was reclassified to NUT carcinoma in order to reflect that it can occur outside midline structures of the body. This case report follows a 43-year-old male presenting with a nasopharyngeal mass invading the frontal brain region, ultimately diagnosed as NUT carcinoma. Here, we detail the clinical and molecular characteristics of this tumor to contribute to the growing body of literature on this rare malignancy, while acknowledging potential diagnostic challenges and therapeutic considerations.

Indexed as

brd4-nutnasopharyngeal cancer (npc)nut carcinomanutm1-brd4 mutationnut midline carcinoma (nmc)

Identifiers

PMID41194824
PMCPMC12585695

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.