ReviewFrontiers in cell and developmental biology2025
Hydrogel based scaffolds in cardiovascular disease: applications in myocardial regeneration, biological pacing, and heart failure therapy.
Review in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Programming the beating heart with polymer catalysis: a therapeutic microenvironment revolution.Journal of nanobiotechnology · 2026Review
- Hydrogels loaded with different substances for treating heart failure: a promising therapy.Frontiers in cardiovascular medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. Current treatments for cardiovascular diseases have improved overall survival rates. However, there are several limitations in reversing left ventricular hypertrophy, preventing ischemia-reperfusion injury, and completely curing refractory heart failure. Tissue engineering, such as the use of hybrid scaffolds, provides a promising strategy for solving these problems and is used in cardiovascular diseases, especially in the treatment of myocardial infarction. Hydrogels are materials with unique 3D crosslinked polymer networks. They are composed of natural or synthetic hydrophilic polymers that contain many chemical components. Hydrogels serve as effective materials in drug delivery and tissue regeneration, achieving desired therapeutic effects for a range of diseases. This review aims to introduce the types of tissue engineering materials currently used, including natural and synthetic hydrogels. In addition, this review investigates the application of hydrogels in cardiovascular diseases such as myocardial infarction, biological pacing, myocardial regeneration, and heart failure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.