Evidence map›Paper›PMID 41196064›Full record

Trial reportNeurosurgery2026

Use of an Expert Panel for Symptomatic Patients With Grade I Degenerative Lumbar Spondylolisthesis: A Randomized Clinical Trial.

Zoher Ghogawala, Tasneem Z Rizvi, Zhibang Lin, Adam Kanter, Praveen V Mummaneni, Erica F Bisson, Todd J Albert, Daniel K Resnick, Michael Y Wang, Steven Glassman and 21 more

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03570801 (SLIP II Registry), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03570801 naactive not recruitingnot on this map

SLIP II Registry: Spinal Laminectomy to Laminectomy With Instrumented Pedicle Screw Fusion for Lumbar Stenosis With Grade I Spondylolisthesis

TypeinterventionalSponsorLahey ClinicRan2017 to 2028Enrolled662ConditionsLumbar Spondylolisthesis, Grade 1 Spondylolisthesis, Lumbar Spinal Stenosis, Degenerative SpondylolisthesisArmsExpert Panel Review
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Zoher GhogawalaDepartment of Neurosurgery, Lahey Hospital and Medical Center, Burlington , Massachusetts , USA.ORCID 0000-0003-1345-1831
Tasneem Z RizviDepartment of Surgery, Lahey Hospital and Medical Center, Burlington , Massachusetts , USA.
Zhibang LinDepartment of Surgery, Lahey Hospital and Medical Center, Burlington , Massachusetts , USA.
Adam KanterDepartment of Neurosurgery, Hoag Neurosciences Institute, Newport Beach , California , USA.
Praveen V MummaneniDepartment of Neurosurgery, University of California San Francisco, San Francisco , California , USA.
Erica F BissonDepartment of Neurosurgery Clinical Neurosciences Center, University of Utah School of Medicine, Salt Lake City , Utah , USA.
Todd J AlbertDepartment of Orthopedic Surgery, Hospital for Special Surgery, New York , New York , USA.
Daniel K ResnickDepartment of Neurosurgery, University of Wisconsin, Madison , Wisconsin , USA.
Michael Y WangDepartment of Neurosurgery, University of Miami, Miami , Florida , USA.
Steven GlassmanDepartment of Orthopedic Surgery, Norton Leatherman Spine, University of Louisville, Louisville , Kentucky , USA.
David W PollyDepartment of Orthopedics, University of Minnesota, St Paul , Minnesota , USA.
Mohamad BydonDepartment of Neurosurgery, University of Chicago, Chicago , Illinois , USA.
Subu N MaggeDepartment of Neurosurgery, Lahey Hospital and Medical Center, Burlington , Massachusetts , USA.
Luis M TumialanDepartment of Neurosurgery, Barrow Brain and Spine Institute, Phoenix , Arizona , USA.
Michael G FehlingsDivision of Neurosurgery, Department of Surgery, University of Toronto, Toronto , Canada.
Michael P SteinmetzDepartment of Neurosurgery, Cleveland Clinic Lerner College of Medicine, Cleveland , Ohio , USA.
Robert G WhitmoreDepartment of Neurosurgery, Lahey Hospital and Medical Center, Burlington , Massachusetts , USA.
Vedantam RajshekharDepartment of Neurosurgery, Christian Medical College Hospital, Vellore , India.
James S HarropDepartment of Neurosurgery, Thomas Jefferson University, Philadelphia , Pennsylvania , USA.
Roger HärtlDepartment of Neurosurgery, Och Spine at New York-Presbyterian/Weill Cornell medical Center, New York , New York , USA.
Elnasri AhmedDepartment of Orthopedics, University Hospitals of North Midlands, Stoke-on-Trent , England.
Dom CoricAtrium Health, Southeast Spine Center of Excellence, Charlotte , North Carolina , USA.
Paul C McCormickDepartment of Neurosurgery, Columbia Presbyterian Hospital, New York , New York , USA.
Richard AssakerDepartment of Orthopedics, Centre Hospitalier Regional Universitaire, Lille , France.
Abdul K MsaddiDepartment of Neurosurgery, Neuro Spinal Hospital, Dubai , United Arab Emirates.
Langston T HollyDepartment of Neurosurgery, University of California Los Angeles, Los Angeles , California , USA.
Yoshiharu KawaguchiDepartment of Orthopedic Surgery, University of Toyama, Toyama , Japan.
Asdrubal FalavignaDepartment of Neurosurgery, Caxias do Sul University, Rio Grande do Sul , Brazil.
Fred G BarkerDepartment of Neurosurgery, Massachusetts General Hospital Brain Tumor Center, Boston , Massachusetts , USA.
Edward C BenzelDepartment of Neurosurgery, Cleveland Clinic Lerner College of Medicine, Cleveland , Ohio , USA.
SLIP II Investigators

Funding

Stuart Foundation 2014 - Alan L. & Jacqueline B. Stuart
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe appropriate utilization of lumbar fusion when performing laminectomy for lumbar spondylolisthesis is uncertain. The objective was to determine whether the use of a surgical expert review panel recommending fusion might improve patient selection, possibly reducing surgical failures.

methodsRandomized clinical trial of patients with symptomatic degenerative lumbar stenosis with spondylolisthesis enrolled from 14 North American hospitals was conducted with patients randomized to receive an expert panel review of their case or not. Spinal expert review consisted of 10 to 15 surgeons' review of patient images and clinical data with voting on the appropriateness of fusion. Primary outcome was the percentage of patients who failed to improve their 1-year EuroQol-5 Dimension (EQ-5D) score. Secondary analysis focused on whether a supermajority (>80% consensus) of spinal experts recommending fusion might reduce operative failures. The trial (SLIP II) was registered at ClinicalTrials.gov (NCT03570801).

resultsBetween November 1, 2017, and June 30, 2022, 663 patients were randomized (mean age 65.6 years; [59.6%] female) and 523 of 574 patients (91%; who had surgery) were included in the 1-year analysis. Final follow-up was on March 5, 2024. Among the 523 patients, 270 underwent review and 253 had no review. The overall surgical failure rate (using EQ-5D) did not differ between the review groups, 16.7% vs 17.4% (no review: difference 0.7%; 95% CI, -8% to 6%; P = .92). However, with supermajority recommending fusion, the proportion of patients who failed to improve EQ-5D score after surgery was 8.4% (review group) vs 18.4% (nonreview group: difference 10%; 95% CI, 2%-18%; P = .03). Supermajority recommendation for fusion was associated with 0.296 vs 0.240 EQ-5D change in the nonreview group (difference 0.056, 95% CI, 0.002-0.108; P = .04).

conclusionAmong patients with grade I degenerative lumbar spondylolisthesis, an expert panel review with a supermajority favoring fusion was associated with a greater improvement in health-related quality of life and fewer surgical failures.

Indexed as

Lumbar VertebraeSpinal FusionSpinal StenosisSpondylolisthesisAgedFemaleHumansLaminectomyMaleMiddle AgedPatient SelectionTreatment OutcomeExpert panelLumbar fusionLumbar laminectomyLumbar spondylolisthesisRandomized clinical trial

Identifiers

PMID41196064
PMCPMC13336581

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.