Evidence map›Paper›PMID 41196405›Full record

ReviewCellular and molecular life sciences : CMLS2025

Towards molecular diagnostics of parental alienation.

Oleksandr Kamyshnyi, Iryna Kamyshna, Pavlo Petakh, Iryna Halabitska, Magnar Bjoras, Valentyn Oksenych, Marie-Pierre Schoving, Denis E Kainov

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Oleksandr KamyshnyiDepartment of Microbiology, Virology, and Immunology, I. Horbachevsky Ternopil National Medical University, Ternopil, 46001, Ukraine.
Iryna KamyshnaDepartment of Medical Rehabilitation, I. Horbachevsky Ternopil National Medical University, Ternopil, 46001, Ukraine.
Pavlo PetakhDepartment of Biochemistry and Pharmacology, Uzhhorod National University, Uzhhorod, Ukraine. pavlo.petakh@uzhnu.edu.ua.ORCID http://orcid.org/0000-0002-0860-4445
Iryna HalabitskaDepartment of Therapy and Family Medicine, I. Horbachevsky Ternopil National Medical University, Ternopil, 46001, Ukraine.
Magnar BjorasDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Valentyn OksenychDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Marie-Pierre SchovingDepartment of Child Psychiatry, Pitié-Salpêtrière, Paris, France.
Denis E KainovDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway. denis.kainov@ntnu.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-conflict parental divorce can result in parental alienation (PA), leading to chronic psychological stress in children that adversely affects their mental and physical health. This stress may manifest as anxiety, depression, eating disorders, immune dysfunction, and cardiovascular, neurological, endocrine, or gastrointestinal issues. The inconsistent legal recognition of PA highlights the need for objective diagnostic tools to inform judicial decisions. We propose a panel of molecular biomarkers, derived from well-established indicators of chronic stress, to address the limited data specific to PA. This panel targets hypothalamic-pituitary-adrenal (HPA) axis activation, neurotransmitter dysregulation, inflammation, oxidative stress, epigenetic modifications, and gut microbiota dysbiosis. Interdisciplinary collaboration among researchers, general practitioners, and legal professionals is crucial to validate and implement this panel, ultimately enhancing child welfare through early intervention.

Indexed as

DivorceParentsStress, PsychologicalBiomarkersChildGastrointestinal MicrobiomeHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemBiomarkersChild healthChronic stressHPA axis dysregulationMolecular diagnosticsParental alienation

Identifiers

PMID41196405
PMCPMC12592572

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.