Evidence mapPaperPMID 41198178Full record

ArticleAddiction (Abingdon, England)2026

Socio-economic differences in the effectiveness of pharmacotherapy use in alcohol use disorder: A cohort study of 148 626 individuals in Sweden.

Devy L Elling, Emelie Thern, Lluís Mangot-Sala, Jari Tiihonen, Anders Hammarberg, Daniel Falkstedt, Heidi Taipale

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Devy L EllingUnit of Occupational Medicine, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-4452-8080
Emelie ThernUnit of Occupational Medicine, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Lluís Mangot-SalaUnit of Occupational Medicine, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Jari TiihonenCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Anders HammarbergCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Daniel FalkstedtUnit of Occupational Medicine, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-4441-7003
Heidi TaipaleDepartment of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland.

Funding

Swedish Alcohol Retail Monopoly Alcohol Research Council FO2022-0044
6 · The paper itself

Abstract

aimTo examine the socioeconomic differences in the effectiveness of alcohol use disorders (AUD) pharmacotherapy and risk of AUD hospitalisation.

designA prospective register-based cohort study.

settingSweden.

participantsIndividuals who were registered as living in Sweden in 2005 (16-64 years) with a first-time AUD diagnosis and complete information on their socioeconomic position (SEP) between 2005 and 2019 (n = 148 626). MEASUREMENT: The outcome was AUD hospitalisation. The use of AUD pharmacotherapy was treated as a time-varying exposure. SEP was the moderator. The association between the joint-exposure (pharmacotherapy use and SEP) and AUD hospitalisation was assessed using a competing-risk regression model, adjusted for sociodemographic factors, previous mental health diagnoses and use of other psychiatric medications.

findingsPharmacotherapy use was associated with a lower risk of AUD hospitalisation among high SEP individuals [subdistribution hazard ratio (SHR) = 0.83, 95% confidence interval (CI) = 0.77-0.90], but not among those with low SEP (SHR = 1.02, 95% CI = 0.94-1.10) and middle SEP (SHR = 1.01, 95% CI = 0.94-1.09), compared with low SEP individuals when not using pharmacotherapy.

conclusionsIn Sweden, alcohol use disorder (AUD) pharmacotherapy appears to be effective to reduce the risk of AUD hospitalisation only among individuals of high socioeconomic position.

Indexed as

Alcohol DeterrentsAlcoholismAlcohol-Related DisordersHospitalizationAdolescentAdultCohort StudiesFemaleHumansMaleMiddle AgedProspective StudiesRegistriesSocioeconomic FactorsSwedenTreatment OutcomeAlcohol Deterrentsalcohol use disordercohort studyhospitalisationjoint exposurepharmacotherapysocio‐economic differences

Identifiers

PMID41198178
PMCPMC12887921

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.