Evidence map›Paper›PMID 41198241›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2026

On Hallucinations in Artificial Intelligence-Generated Content for Nuclear Medicine Imaging (the DREAM Report).

Menghua Xia, Reimund Bayerlein, Yanis Chemli, Xiaofeng Liu, Jinsong Ouyang, MingDe Lin, Georges El Fakhri, Ramsey D Badawi, Quanzheng Li, Chi Liu

Abstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Menghua XiaDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut.
Reimund BayerleinDepartment of Biomedical Engineering, University of California Davis, Sacramento, California.
Yanis ChemliDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut.
Xiaofeng LiuDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut.
Jinsong OuyangDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut.
MingDe LinDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut.
Georges El FakhriDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut.
Ramsey D BadawiDepartment of Biomedical Engineering, University of California Davis, Sacramento, California.
Quanzheng LiDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Chi LiuDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut; chi.liu@yale.edu.

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI KC KENT LLOYD · 2002 to 2026
$84.9M
Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Georges El Fakhri · 2017 to 2026
$14.8M
Multi-Center Academic-Industrial Partnership for Personalized Al-Enabled High Count PETR01CA275188 · NCI · YALE UNIVERSITY · PI RAMSEY D. BADAWI, Georges El Fakhri · 2023 to 2026
$2.5M
Deep learning-based target volume delineation capturing observer variability in head and neck cancerR01CA290745 · NCI · YALE UNIVERSITY · PI Georges El Fakhri · 2024 to 2026
$1.7M
NCI NIH HHS P30 CA093373NCI NIH HHS R01 CA275188NCI NIH HHS R01 CA290745NIBIB NIH HHS P41 EB022544
6 · The paper itself

Abstract

Artificial intelligence-generated content (AIGC) has shown remarkable performance in nuclear medicine imaging (NMI), offering cost-effective software solutions for tasks such as image enhancement, motion correction, and attenuation correction. However, these advancements come with the risk of hallucinations, generating realistic yet factually incorrect content. Hallucinations can misrepresent anatomic and functional information, compromising diagnostic accuracy and clinical trust. This paper presents a comprehensive perspective on hallucination-related challenges in AIGC for NMI, introducing the DREAM report, which covers recommendations for definition, representative examples, detection and evaluation metrics, and attributions and mitigation strategies. This position statement paper aims to initiate a common understanding for discussions and future research toward enhancing AIGC applications in NMI, thereby supporting their safe and effective deployment in clinical practice.

Indexed as

Artificial IntelligenceDiagnostic ImagingHallucinationsNuclear MedicineHumansImage Processing, Computer-AssistedAIGCartificial intelligence–generated contenthallucinationNMInuclear medicine imaging

Identifiers

PMID41198241
PMCPMC12866389

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.