Evidence mapPaperPMID 41199083Full record

ArticleMolecular neurobiology2025

High-Fat Diet Exacerbates Behavioral and Neurochemical Deficits in BTBR Mice: Linking Intestinal Inflammation and Brain Neurotransmitter Dysregulation to Melatonin Therapeutic Potential.

Qiuping Yang, Meng Cai, Ximei Yang, Zao Liang, Bingqing Liu, Wenting Gan, Wei Liu, Yao Cai, Xin Xiao

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qiuping Yang *Department of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Meng Cai *Department of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Ximei Yang *Department of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Zao LiangDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Bingqing LiuDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Wenting GanDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.
Wei LiuDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China. liuw327@mail.sysu.edu.cn.
Yao CaiDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China. caiy33@mail.sysu.edu.cn.
Xin XiaoDepartment of Pediatrics, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China. xiaoxin2@mail.sysu.edu.cn.

Funding

Administration of Traditional Chinese Medicine of Guangdong Province, China 20231060Medical Scientific Research Foundation of Guangdong Province, China A2022066Science and Technology Program of Guangzhou, China 202103000071
6 · The paper itself

Abstract

This study aims to investigate the effects of high-fat diet (HFD) on behavioral symptoms, brain neurotransmitters and intestinal inflammation in autism spectrum disorders (ASD) model mice-BTBR T

Indexed as

Behavior, AnimalBrainDiet, High-FatInflammationIntestinesMelatoninNeurotransmitter AgentsAnimalsAnxietyAutism Spectrum DisorderMaleMiceMice, Inbred C57BLSerotoninMelatoninNeurotransmitter AgentsSerotonin5-hydroxytryptamineAutism spectrum disordersDopamineGut inflammationHigh-fat dietMelatonin

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.