Evidence mapPaperPMID 41199126Full record

ArticlePharmacological reports : PR2026

The application of machine learning in the evaluation of urinary tract infections incidence in patients in a Nursing and Treatment Facility.

Urszula Grzegorzek, Joanna Sobiak, Ewa Jaworucka, Bartosz Sznek, Andrzej Czyrski

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Article in Pharmacological reports : PR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Urszula Grzegorzek *Hospital Pharmacy at County Hospital, Piłsudskiego 8, Drezdenko, 66-530, Poland.
Joanna Sobiak *Department of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, Rokietnicka 3 Street, Poznań, 60-806, Poland.ORCID http://orcid.org/0000-0002-2764-1575
Ewa JaworuckaNursing and Treatment Facility, County Hospital, Piłsudskiego 8, Drezdenko, 66-530, Poland.
Bartosz SznekDepartment of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, Rokietnicka 3 Street, Poznań, 60-806, Poland.ORCID http://orcid.org/0009-0001-3536-0079
Andrzej CzyrskiDepartment of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, Rokietnicka 3 Street, Poznań, 60-806, Poland. aczyrski@ump.edu.pl.ORCID http://orcid.org/0000-0003-1581-8326

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrinary tract infection (UTI) is a serious problem in the healthcare system. It is caused by bacteria from the gastrointestinal tract. The risk factors that impact the UTI incidence include administration of certain drugs (flozins), sex, use of urinary catheter, and diabetes. This is a retrospective study of the records of 76 patients from a Nursing and Treatment Facility at County Hospital in Drezdenko (Poland) aimed to assess the factors that may have an impact on the incidence of UTI.

methodsThe following factors were taken into consideration: dapagliflozin administration (yes/no), diabetes (yes/no), sex (male/female), kidney failure (yes/no), and use of urinary catheter (yes/no). The impact of the above variables on the UTI incidence was estimated using multivariate regression analysis and machine learning, such as logistic regression, artificial neural networks (ANN), and decision trees (recursive partitioning).

resultsAs revealed by the multivariate regression analysis, UTI was significantly affected only by dapagliflozin administration. The machine learning techniques showed greater sensitivity in detecting significant factors - dapagliflozin administration was identified as the most important one. Moreover, the logistic regression analysis also indicated sex (female). In the case of ANN and decision tree, the other significant factors, besides dapagliflozin intake, in the model were the use of a urinary catheter, sex (female), diabetes, and kidney failure (in descending importance). The variables were listed in the same order of descending importance for both the ANN and the decision tree.

conclusionsIn the case of catheterized patients, the administration of flozins should be cautiously approached, as should the catheterization of patients taking flozins. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Machine LearningUrinary Tract InfectionsAdultAgedAged, 80 and overBenzhydryl CompoundsFemaleGlucosidesHumansIncidenceMaleMiddle AgedNeural Networks, ComputerRetrospective StudiesRisk FactorsBenzhydryl CompoundsdapagliflozinGlucosidesArtificial neural networksDapagliflozinDecision treeLogistic regressionRecursive partitioning

Identifiers

PMID41199126
PMCPMC12795950

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.