Evidence map›Paper›PMID 41199187›Full record

ArticleBMC genomics2025

Why the lipid deposition in the muscle fibers and myosepta is selective in triploid rainbow trout? A lncRNA‒mRNA study.

Qianwen Li, Falie Shi, Guoliang Sun, Fulei Wei, Zezhong Wu, Rui Ma, Yuqiong Meng

Abstract read
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qianwen LiCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, 810016, China.
Falie ShiCold-Water Fish Research Center, State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, 810016, China.
Guoliang SunCold-Water Fish Research Center, State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, 810016, China.
Fulei WeiKey Laboratory of Plateau Cold-Water Fish Culture and Eco-Environmental Conservation (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Xining, 810016, China.
Zezhong WuCold-Water Fish Research Center, State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, 810016, China.
Rui MaCold-Water Fish Research Center, State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, 810016, China. myrui713@163.com.
Yuqiong MengCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, 810016, China. yuqiongcheer@163.com.

Funding

National Natural Science Foundation of China No. 32360919Natural Science Foundation of Qinghai Province 2023-ZJ-912MQinghai University Research Ability Enhancement Project 2025KTSQ19
6 · The paper itself

Abstract

Salmonids can accumulate lipids in their fillets, creating marbled features with alternate red (Muscle Fibers, MF) and white stripes (Myosepta, MS). To investigate the regulation of this important quality trait, diets with low and high lipid levels were fed to the fish and found that high lipid diet significantly elevated muscular lipid deposition in MS but not in MF. Then, a whole-transcriptome analysis was performed and results showed that the mRNA expression of ACSL1 and GADD45A was downregulated by the lncRNAs MSTRG.19477.1 and XR_005039693.1, resulting in consistent lipid contents in the MF from both groups. The lncRNAs MSTRG.21618.1, XR_005034756.1, XR_002473790.2, XR_002472790.2, and MSTRG43906.1 increased lipid deposition in MS30 by upregulating the mRNA expression of ELOVL2, DGAT2, LCAT, etc. In conclusion, the present study revealed that selective muscular lipid deposition and several lncRNAs may play key roles in regulating the marbling features of rainbow trout.

Indexed as

Lipid MetabolismMuscle Fibers, SkeletalOncorhynchus mykissRNA, Long NoncodingRNA, MessengerTriploidyAnimalsFish ProteinsGene Expression ProfilingFish ProteinsRNA, Long NoncodingRNA, MessengerLipid depositionlncRNAsMuscle fiberMyoseptaTriploid rainbow trout

Identifiers

PMID41199187
PMCPMC12593845

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.