Evidence map›Paper›PMID 41199615›Full record

SynthesisAnaesthesia2026

A core outcome set for airway management research.

Jan Hansel, Alexander Fuchs, Benjamin Cornwell, Katherine Haynes, Vinay Tanna, Ahmed Mohamed, Kate Rivett, Gillian Radcliffe, Robert Greif, Tim M Cook and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jan HanselDivision of Immunology, Immunity to Infection and Respiratory Medicine, The University of Manchester, Manchester, UK.ORCID 0000-0003-2858-1313
Alexander FuchsDepartment of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0001-7188-1683
Benjamin CornwellDepartment of Anaesthesia, Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.
Katherine HaynesDepartment of Anaesthesia and Perioperative Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Vinay TannaCritical Care, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
Ahmed MohamedIntensive Care Unit, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, UK.
Kate RivettDifficult Airway Society, London, UK.
Gillian RadcliffeDepartment of Anaesthesia and Perioperative Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0003-4870-6339
Robert GreifFaculty of Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0003-0160-2073
Tim M CookDepartment of Anaesthesia, Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.ORCID 0000-0002-3654-497X
Kariem El-BoghdadlyDepartment of Anaesthesia and Perioperative Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0002-9912-717X
Airway Terminology and Outcome Measures (ATOM) Collaborators

Funding

Association of Anaesthetists WKR0-2023-0006Inselspital, Universitätsspital Bern FUAD-2-24
6 · The paper itself

Abstract

introductionAirway management research has historically incorporated heterogeneous outcome selection and definitions. This impedes evidence synthesis and hinders advances in patient care. We aimed to develop a core outcome set to standardise airway management research and improve outcome reporting.

methodsWe performed a systematic review of outcomes reported in airway management studies to identify candidate outcomes from a random sample of eligible studies. We used a modified Delphi survey of three key stakeholder groups: patients with experience of airway management; clinicians engaged in airway management; and others (including researchers, device manufacturers and policymakers). Outcomes were classified into five domains: procedural effectiveness; physiological parameters; adverse events; patient-reported outcomes; and other. Outcomes were presented in random order in two sequential virtual Delphi surveys and rated by each respondent. Candidate outcome measurement instruments were identified through included studies and targeted literature searches. Subsequently, a core outcome set with suggested outcome measurement instruments was discussed and agreed.

resultsThe systematic review identified 4368 studies, with 68 candidate outcomes longlisted from a random sample of 100 studies. Rounds one and two Delphi surveys were completed by 453 and 155 participants, respectively, from six continents. First and second virtual panels were attended by 62 and 44 participants, respectively. The final agreed core outcome set included 11 outcomes: death; cardiac arrest; serious complications; pulmonary complications; neurological complications; airway trauma; unrecognised oesophageal intubation; hypoxaemia; first attempt success without complications; overall success without complications; and difficult airway. Proposed outcome measurement instruments were agreed for all included outcomes. DISCUSSION: We present the first consensus-based core outcome set for airway management research, with agreed definitions and measurement instruments. Incorporation of these outcomes into future airway management studies will harmonise evidence synthesis and improve the translatability of findings to improve clinical care.

Indexed as

Airway ManagementOutcome Assessment, Health CareDelphi TechniqueHumansairway managementcore outcome setpatient‐reported outcomessurvey

Identifiers

PMID41199615
PMCPMC12893836

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.