Evidence map›Paper›PMID 41200065›Full record

ReviewOncology letters2026

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review).

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu

Abstract readReview
In one paragraph

Review in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengli ChenDepartment of Laboratory Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, P.R. China.
Feng WangDepartment of Laboratory Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, P.R. China.
Weixi WangDepartment of Laboratory Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, P.R. China.
Kangle FengDepartment of Laboratory Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, P.R. China.
Kaihua XiangDepartment of Laboratory Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, P.R. China.
Xubo GongDepartment of Laboratory Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, P.R. China.
Zhihua TaoDepartment of Laboratory Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, P.R. China.
Weiwei LiuDepartment of Laboratory Medicine, Zhejiang University School of Medicine Second Affiliated Hospital, Hangzhou, Zhejiang 310009, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) remains among the most common genitourinary tumors in elderly men, as PCa diagnosis and treatment remain major challenges. Liquid biopsy is a minimally invasive method that causes minor harm to patients with cancer. Peripheral blood protein biomarkers provide real-time PCa information and are easily accessible. The present review summarizes recent progress in identifying candidate peripheral blood protein biomarkers of PCa, including pentraxin-3, soluble E-cadherin, serum T-cell immunoglobulin, serum B- and T-lymphocyte attenuator, myeloid differentiation factor-2, pleiotrophin, spondin 2, filamin A, soluble urokinase plasminogen activator receptor, laminin subunit β-1, Golgi membrane protein 1, vitamin D-binding protein, tumor necrosis factor receptor superfamily member 9, activated leukocyte cell adhesion molecule and trophoblastic cell-surface antigen. Notably, the present review summarizes and discusses the clinical value of these proteins in PCa prediction, diagnosis, prognosis and drug resistance monitoring. These emerging peripheral blood protein biomarkers are promising for improving PCa stratification and management.

Indexed as

diagnostic valuedrug resistance monitoring valueperipheral blood protein biomarkerspredictive valueprognostic valueprostate cancer

Identifiers

PMID41200065
PMCPMC12587114

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.