ArticleFrontiers in medicine2025
Clinical features and outcomes of pregnancies complicated by coexisting gestational diabetes and hypertensive disorders.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Reduced serum acetyl-L-carnitine is associated with hypertensive disorders in women with gestational diabetes mellitus: a multi-omics study.Cardiovascular diabetology · 2026Article
- Association of pre-pregnancy abnormal glucose metabolism and insulin resistance with assisted reproductive technology outcomes and pregnancy complications in women with PCOS: a retrospective propensity score matching study.BMC pregnancy and childbirth · 2026Article
- Characteristics of Placental Bacterial DNA Communities in Pregnant Women with Gestational Diabetes Mellitus and Association with Early Neonatal Gut Microbiota and Short-Term Perinatal Outcomes.Polish journal of microbiology · 2026Article
- Windows of susceptibility to fine particulate matter components for fetal birth weight: a birth cohort study.BMC public health · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Gestational diabetes mellitus (GDM) and hypertensive disorder complicating pregnancy (HDP) share pathophysiological mechanisms that increase the risk for adverse maternal and neonatal outcomes. However, their combined impact remains underexplored. Objective: To assess the clinical characteristics, therapeutic interventions, and maternal-fetal outcomes in pregnancies complicated by both GDM and HDP. Methods: A retrospective study was conducted involving 82 women with GDM complicated by HDP and 118 healthy pregnant controls. Clinical parameters, mode of delivery, and pregnancy outcomes were compared between groups. Logistic regression analysis was performed to identify independent predictors of GDM complicated by HDP. Results: Women with GDM complicated by HDP exhibited significantly higher pre-pregnancy weight, body mass index (BMI), fasting blood glucose, triglycerides, and high-density lipoprotein (HDL) cholesterol compared with healthy controls ( Conclusion: Pre-pregnancy metabolic factors, including BMI, fasting blood glucose, triglycerides, and HDL cholesterol, are strong predictors of GDM complicated by HDP. Early identification and individualized management of these high-risk pregnancies can effectively reduce adverse maternal and neonatal outcomes.
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