ArticlePLoS neglected tropical diseases2025
Clinical and laboratory factors associated with scrub typhus and hemorrhagic fever with renal syndrome in Southwestern Korea: A cross-sectional study.
Article in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundScrub typhus and Hemorrhagic fever with renal syndrome (HFRS) are prevalent infectious diseases in South Korea. This study compared the clinical and laboratory characteristics associated with scrub typhus and HFRS treated at Chosun University Hospital, South Korea. METHOD/
findingsA retrospective cross-sectional study was conducted by reviewing the medical records of patients diagnosed with scrub typhus and HFRS between 2010 and 2023. Diagnoses were confirmed through molecular and serological testing. A total of 156 patients with scrub typhus and 45 patients with HFRS were included. Among patients with scrub typhus, 136 (87.18%) patients had Boryong strain, 4 (2.56%) had Taguchi strain, 3 (1.93%) had Karp strain, and 1 (0.64%) had Kanda strain. Most cases of scrub typhus and HFRS occurred in individuals aged ≥65 years. The common clinical features of scrub typhus included fever, fatigue, skin rash, and eschar. In contrast, HFRS commonly presented with fever, gastrointestinal symptoms, and hemorrhagic manifestations. The mean hospital stay was significantly longer for HFRS (14.09 ± 7.67 days) compared to scrub typhus (7.89 ± 7.56 days, p < 0.001). A higher proportion of patients with HFRS (15, 33.33%) required intensive care unit admission compared to patients with scrub typhus (14, 8.97%, p < 0.001). Among patients with scrub typhus, the adjusted odds of presenting with a skin rash, eschar, or lymphopenia (<1500/µL) were 1.37 (95% confidence interval [CI]: 1.18-1.59, p < 0.001), 1.25 (95% CI: 1.11-1.40, p < 0.001), and 1.83 (95% CI: 1.34-2.49, p < 0.001), respectively.
conclusionsWhile scrub typhus and HFRS share overlapping clinical features, skin rash, eschar, and lymphopenia were more commonly associated with scrub typhus. Further studies are warranted to characterize clinical features and outcomes of various hantavirus subtypes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.