Evidence map›Paper›PMID 41202149›Full record

ArticleScience immunology2025

T

Martina Zoccheddu, Kensuke Suga, Amara Seng, Mattias N D Svensson, Paramita Dutta, Sanaz Panahandeh, Hadijat-Kubura Moradeke Makinde, Myungja Ro, Yizhou Wang, Hyobin Kim and 23 more

Abstract read
In one paragraph

Article in Science immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. ExTNature reviews. Rheumatology · 2026
    Article
  6. Article
  7. AFrontiers in tuberculosis · 2026
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Martina ZocchedduDepartment of Medicine, Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-1631-0866
Kensuke SugaDepartment of Medicine, Kao Autoimmunity Institute and Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0003-3107-788X
Amara SengDepartment of Medicine, Kao Autoimmunity Institute and Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0001-7077-5969
Mattias N D SvenssonDepartment of Medicine, Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-8077-9824
Paramita DuttaCenters for Autoimmunity, Inflammation and Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Sanaz PanahandehDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0001-9253-4891
Hadijat-Kubura Moradeke MakindeDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0001-8492-4187
Myungja RoDepartment of Medicine, Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA 92093, USA.
Yizhou WangDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0002-9378-745X
Hyobin KimDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0002-4856-7415
Zbigniew MikulskiHistology and Microscopy Core Facility, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.ORCID 0000-0002-1918-9216
Katarzyna DobaczewskaHistology and Microscopy Core Facility, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.ORCID 0000-0002-6377-018X
Francesca IngegnoliClinical Rheumatology Unit, ASST Gaetano Pini-CTO, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.ORCID 0000-0002-6727-1273
Ruth MinshaDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
John F SeagristDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0009-0000-3629-1530
Mary CarnsDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-5063-156X
Kathleen ArenDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0003-4770-2643
Salina DominguezDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0009-0002-2659-7610
Mohammad Daud KhanDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Angela DennHistology and Microscopy Core Facility, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.ORCID 0000-0002-1844-4668
Roberto CaporaliClinical Rheumatology Unit, ASST Gaetano Pini-CTO, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Pietro Simone Randelli1st Orthopedic Unit, ASST Gaetano Pini-CTO, Lab of Applied Biomechanics, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.ORCID 0000-0001-9331-820X
David A McBrideDepartment of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-7695-5178
Arthur M MandelinDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Carla Marie CudaDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-2022-8171
Zhiping Paul WangDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0002-3796-3164
Jason H MooreDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0002-5015-1099
Nisarg J ShahDepartment of Nanoengineering, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-1727-5732
Kyoung Jae WonDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0002-2924-9630
Deborah R WinterDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0003-1806-673X
Ferhat AyCenters for Autoimmunity, Inflammation and Cancer Immunotherapy, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.ORCID 0000-0002-0708-6914
Harris PerlmanDepartment of Medicine, Division of Rheumatology Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Nunzio BottiniDepartment of Medicine, Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-9025-7501

Funding

Role of PTPRS in Rheumatoid ArtiritisR01AR066053 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BOTTINI, NUNZIO · 2014 to 2025
$4.0M
Macrophage Heterogeneity in Rheumatoid ArthritisR01AR080513 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Harris R Perlman, Deborah Rachelle Winter · 2022 to 2026
$3.3M
Multidisciplinary Pulmonary Research Training ProgramT32HL170963 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI PETER CHEN · 2024 to 2026
$986k
NovaSeq5000 High Throughput SequencerS10OD025052 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SEUMOIS, GREGORY · 2018 to 2018
$832k
Super-resolution confocal microscopeS10OD021831 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI LEY, KLAUS F. · 2017 to 2017
$566k
FACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514k
Functional plasticity of Th17 in arthritisR21AI154964 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BOTTINI, NUNZIO · 2020 to 2021
$434k
NCRR NIH HHS S10 RR027366NHLBI NIH HHS T32 HL170963NIAID NIH HHS R21 AI154964NIAMS NIH HHS R01 AR066053NIAMS NIH HHS R01 AR080513NIH HHS S10 OD021831NIH HHS S10 OD025052
6 · The paper itself

Abstract

T helper 17 (T

Indexed as

Arthritis, ExperimentalArthritis, RheumatoidInterleukin-17Th17 CellsAnimalsCell TransdifferentiationFemaleHumansHyaluronan ReceptorsInflammationMaleMiceSynovial MembraneSynoviocytesHyaluronan ReceptorsInterleukin-17

Identifiers

PMID41202149
PMCPMC13001110

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.